Onward Phytochemicals, Onward!

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There are lots of ways you can improve your health; eat better, exercise, getting plenty of rest, but what’s the best thing you can do? Dr. Fuhrman tells us:

The most powerful thing you can do to improve your health is to eat more green vegetables. Americans eat a piddling amount of greens. If they ate a lot more, disease rates of all types would plummet. Not only are vegetables rich in vitamins and minerals, they also contain thousands of phytochemicals that are critically important for our health.

For real, green vegetables are strong mojo and—quite frankly—green vegetables are nutritional rock stars. Just look at them:



Now, back to the phytochemicals. Stan Kent from Healthy Eating loves phytonutrients! From his post, Phytonutrients Are The New Direction For Healing:

Phytonutrients in vegetables are probably the best hope for stopping some of the most deadly and stubborn diseases.(Newsweek magazine). I have witnessed that as well. These remarkable compounds have nothing in common with the vitamins, supplements and so-called "natural" products sold in health stores, drug stores or on the internet. Most ordinary supplements and vitamins, like pharmaceuticals are totally synthetic. Isolating chemicals is not the same as the combination provided by nature in the foods we eat. What are Phytonutrients?


Phytonutrients are therapeutic foods that are grown, harvested and properly produced without heat. They are a complex combination of plant-based phytochemicals, enzymes, vitamins and minerals. My "Nutrition-Based-Regimen" is based on the herbs vitamins and minerals - what they do for you and what foods to eat to get them. The practice of using phytonutrients to heal may be on the cutting edge of medical science.

Dr. Fuhrman would agree. Phytonutrients and phytochemicals are the next great discovery in health. He talks about it:

We are on the verge of a revolution. Substances newly discovered in broccoli cabbage sprouts sweep toxins out of cells. Substances found in nuts and beans prevent damage to our cells' DNA. Other compounds in beets, peppers, and tomatoes fight cancerous changes in cells. Oranges and apples protect our blood vessels from damage that could lead to heart disease. Nature's chemoprotective army is alert and ready to remove our enemies and shield us from harm.


Hardly a day goes by when some new study doesn't proclaim the health-giving properties of fruits, vegetables, and beans. Unprocessed plant foods contain thousands of compounds, most of which have not yet been discovered, that are essential for maintaining health and maximizing genetic potential. Welcome to the phytochemical revolution.

Here is just a short list of the amazing things plant nutrients can do for you. Check it out:

  • Halt the growth of breast cancer cells, 1
  • Dramatically reduce the risk of colon cancer, 2
  • Prevent the replication of prostate cancer cells and induce death of cancerous cells, 3
  • Inhibit the progression of lung cancer, 4
Okay, I’m pumped up—WHERE’S MY BROCCOLI!

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Inhaled Insulin, Lung Cancer Risk

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Pfizer has announced that clinical trials of Exubera resulted in increased cases of lung cancer. Lewis Krauskopf of Reuters is on it:

Pfizer Inc and Nektar Therapeutics said on Wednesday clinical trials of the inhaled insulin Exubera found increased cases of lung cancer, leading Nektar to stop seeking a marketing partner for the troubled product and abandon it.

Nektar shares tumbled 25 percent, while shares of MannKind Corp, which has been developing its own inhaled insulin, plummeted 58 percent. Pfizer was down slightly at $20.90.

The lung-cancer revelation dealt a final setback to Exubera, which held the promise of letting diabetics avoid needle sticks and was once projected by Pfizer to be a $2 billion-a-year blockbuster. Instead, Exubera has been a commercial flop that has sullied the inhaled insulin field.

Scary, but not that surprising, because—good or bad—Dr. Fuhrman insists all drugs futz with the normal functioning of the body:

In the first pharmacology lecture that I head in medical school, the physician impressed on us that all drugs are toxic and we should never forget this. We were taught that medications work because of their pharmacologic properties—properties that enable the substance to interfere with, block, or stimulate an activity of the body. Drugs typically modify the way the body expresses the signs and symptoms of disease, but in chronic disease states, they do no undo the damage or remove the disease.

My suspicion is this concept often more often than not, takes a backseat to the pursuit of profits and convenience.

Health Points: Friday

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The Food and Drug Administration listed poor sanitation and other deficiencies in 47% of 199 inspections from January 2001 to February 2007, according to a report by the House Oversight and Government Reform Committee. None of the cases was referred to the FDA's enforcement arm for further action.

E. coli bacteria in bagged spinach from California killed three people and sickened at least 205 in 2006. The spinach may have been tainted when feral pigs roamed through cattle feces at a nearby ranch and crossed into the spinach fields, investigators from the FDA and California said last year.

The best that Dr. Julie Gilchrist, a medical epidemiologist at the Centers for Disease Control and one of the study’s authors, can offer is a few guidelines and observations about why studies have yet to answer the stretching questions.


If your goal is to prevent injury, Dr. Gilchrist said, stretching does not seem to be enough. Warming up, though, can help. If you start out by moving through a range of motions that you’ll use during activity, you are less likely to be injured.

In fact, Dr. Gilchrist said, in her review of published papers, every one of the handful of studies that concluded that stretching prevented injuries included warm-ups with the stretches.

The legislation is aimed at curbing the fallout from Americans' unhealthy eating habits, seen in rising rates of obesity and Type 2 diabetes. The hope is that the labels will help people make healthier choices when they're eating out.


But dozens of studies have produced mixed results on whether nutrition labeling improves consumers' eating habits. It can't hurt to make the information available, nutritionists say, however, the truth is, if people want a Big Mac for lunch, knowing that it has 540 calories and 29 grams of fat probably isn't going to stop them.

Scientists said they, too, are concerned about the findings of the water testing commissioned by the Associated Press, but several said that there is no need for people to stop drinking tap water.


The contaminants present are "in the parts-per-billion level and essentially at homeopathic doses," said Phyllis Gardner, a Stanford University physician and pharmacologist. "It can't possibly have an effect."

The fact that the substances are in tap water at all concerns Gardner and others. "I wish they weren't there," said Mary Vore, a professor of toxicology at the University of Kentucky. "But I will keep drinking the water."

New rules announced by the U.S. Environmental Protection Agency will tighten air quality standards set a decade ago, reflecting a growing amount of research indicating that smog poses greater health risks than previously thought.


The air in Chicago, which met federal smog standards for the first time last year, will fail again under the new limit.

Under the regulations outlined by top EPA officials, the allowable level of smog in the air will be 75 parts per billion, down from the current standard of 85 parts per billion but higher than 60 parts per billion recommended by pediatricians and environmental groups to protect children and the elderly.

A recent study of the PACE (People with Arthritis Can Exercise) program by researchers at the University of North Carolina showed significant improvements in reducing pain and fatigue among those who completed the eight-week course, with benefits persisting for up to six months after completion of the course.


"I liked it because it's not just an exercise program," said Laurie Maietta, who taught the PACE course last fall at Panther Physical Therapy in Hampton. "You have the exercise program, an educational program, and a relaxation component as well."

Arthritis sufferers tend to be less fit than seniors who don't suffer from this condition. Which is too bad, said Dr. Moira Davenport, director of sports and emergency medicine for Allegheny General Hospital, because "exercise can definitely help people suffering from arthritis. It strengthens the muscle around the affected joints, and takes away some of the pressure and pain."

The study, by researchers at the U.S. National Cancer Institute, found that men and women who were severely obese were 45 percent more likely than normal-weight adults to develop pancreatic cancer over five years…


…Pancreatic cancer is difficult to catch early, and 95 percent of patients die within five years of being diagnosed. Because of this dismal prognosis, researchers consider it particularly important to pinpoint the modifiable risk factors for the disease.

In many ways, pediatricians do know more than parents. When your doctor says your newborn needs to ride in a rear-facing car seat, don't argue. When he says your 2-month-old with a 105-degree fever needs to get to the doctor's office -- and fast -- you'd better listen.


But there are far more areas that are gray and have no science, or not very good science, to back them up, says our panel of pediatric experts. They say that sometimes, this means your pediatrician is giving you his or her opinion, not medical fact.

"There are several ways to approach many issues in pediatrics. There isn't one clear-cut way," says Dr. Robert Needlman, co-author of the latest edition of "Dr. Spock's Baby and Child Care." "Pediatricians really should make a distinction between what's based on research and what's based on our own particular beliefs."

The U.S. federal standards for acceptable levels of pharmaceutical residue in bottled water are the same as those for tap water -- there aren't any.


The Food and Drug Administration, which regulates the $12 billion bottled water industry in the United States, sets limits for chemicals, bacteria and radiation, but doesn't address pharmaceuticals.

Some water that's bottled comes from pristine, often underground rural sources; other brands have a source no more remote than local tap water. Either way, bottlers insist their products are safe and say they generally clean the water with advanced treatments, though not explicitly for pharmaceuticals.

Tests on mice show that diacetyl, a component of artificial butter flavoring, can cause a condition known as lymphocytic bronchiolitis, said the team at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.


The condition can lead to obliterative bronchiolitis -- or "popcorn lung" -- a rare and debilitating disease seen in workers at microwave popcorn packaging plants and at least one consumer.

At least two microwave popcorn makers -- ConAgra Foods Inc and Weaver Popcorn Co Inc -- have said recently they would stop using diacetyl.

Sunlight Fights Cancer

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Wait, sufficient sun exposure helps prevent disease—NO—you don’t say? Pardon my smart-alecky tone, but this factoid is an old hat for DiseaseProof. Let’s review. Alright, remember this report, Sunlight in Youth Might Shield Against MS? Here’s a refresher:

"Evidence is building up that something in relation to sunlight and/or vitamin D exposure during childhood may play a protective role," said study co-author Dr. Thomas M. Mack, of the department of preventive medicine, Keck School of Medicine, University of Southern California, Los Angeles. "It's now been suggested by several different studies that this is the case, and if it's true, it would be important."

Okay, okay. That’s Multiple Sclerosis, but what about cancer? Is it possible that something as simple as basking in the sun can reduce our risk of developing something as insidious as CANCER? More learning tree time, remember Ultraviolet: Go into the Light? Take a look:

In two studies with mice, a British team cloaked antibodies -- the immune system proteins that tag germs and cancer cells for elimination -- with an organic oil that blocked them from reacting until illuminated with ultraviolet light.


The researchers used engineered immune system proteins called monoclonal antibodies. They are made to home in on proteins known to be overactive in tumor cells.

When the light unblocked the organic coating, the antibodies switched on and attracted killer T-cells to attack the tumor, said Colin Self, a researcher at Newcastle University, who led the studies.

Still not convinced? Alright, I’ve got a new report for you. Amanda Gardner of HealthDay News brings this to the table, under the catchy title, Sunlight Helps Put Lung Cancer in the Shade. Lung cancer too? Yup, lung cancer too! For real, from the report:

A new study finds that lower levels of the sun's ultraviolet B (UVB) rays are associated with a higher incidence of lung cancer across 111 countries.


Still, that doesn't mean that spending more time in the sun will ever offset the risks that come with smoking, according to the study, which is published in the January issue of the Journal of Epidemiology and Community Health.

It's also not an excuse to trade skin cancer for lung cancer.

"The problem is that people might over-interpret this and stay in the sun for hours," said Cedric Garland, study senior author, professor of family and preventive medicine at the University of California, San Diego (UCSD), and participating member at the Moores UCSD Cancer Center in La Jolla.

“For over 60 years, researchers have observed an inverse association between sun exposure and cancer mortality,” explains Dr. Fuhrman,” And those with more sun exposure had fewer cancers.” See, not exactly new news, but how many people listen? That’s the question!

Meat Ups Lung Cancer Risk

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Alright, if you Eat to Live, you probably get this question a lot, “So, what are you vegan?” For me, the answer is no—I eat fish—because according to Dr. Fuhrman a near-vegetarian diet and a vegetarian diet are pretty similar. Here’s a quote:

Is a vegetarian diet healthier than a diet that contains a small amount of animal products? We do not know for sure. The preponderance of evidence suggests that either a near-vegetarian diet or a vegetarian diet is the best, especially for patients with heart disease. In the massive China-Oxford-Cornell Project, reduction in heart disease and cancer rates continued to be observed as participants reduced their animal-food consumption all the way down to 1.7 small servings per week. Under this level, there is not enough data available.

And, meat isn’t all bad. Vegans you might want to pay attention to this post, The Healthy Way to Integrate Meat Into Your Diet, it’ll help you figure out what supplements you need to ensure you’re probably nourished. Some points of interests:

  • Plant foods do not contain B12 (all vegans should take B12).
  • Some people have a need for more taurine, and may not get optimal amounts with a vegan diet. (Some vegans need to take a taurine supplement, or they could get a blood test to assure adequacy).
  • Some vegans may not produce ideal levels of DHA fat (from the conversion of short-chain omega-3 fats) found in such foods as flax and walnuts, if they don't eat fish. I advocate that vegans and people who do not eat fish should supplement with DHA or get a blood test to assure adequacy.
But the problem is—and Dr. Fuhrman would agree—people go berserk with the whole protein thing, especially animal protein. So, this begs the question, Do You Need Animal Protein? Dr. Fuhrman discusses it here:

Today, the average American consumes 100 to 120 grams of protein per day, mostly in the form of animal products. People who eat a completely vegetarian diet (vegan) have been found to consume sixty to eighty grams of protein a day, well above the minimum requirement.1 Vitamin B12, not protein, is the missing nutrient in a vegan diet.


In modern times, the plant foods we eat are well washed and contain little bacteria, bugs, or dirt, which would have supplied B12 in a more natural environment such as the jungle or forest. To assure optimal levels of B12 in our diet, we require some form of B12 supplementation when eating a diet with little or no animal products.

Now eating too much animal protein—or meat—can usher in a lot of serious health problems; most notably cancer and heart disease. Dr. Fuhrman briefly talks about the cancer-heart disease-meat connection here. Take a look:

Plasma apolioprotein B is positively associated with animal-protein intake and inversely associated (lowered) with vegetable-protein intake (e.g., legumes and greens). Apolioprotein B levels correlate strongly with coronary heart disease.2


A recent study from New Zealand that investigated heterocyclic amines in meat, fish, and chicken found the greatest contributor of HCAs to cancer risk was chicken.3

Dr. Fuhrman isn’t the only one talking about the link between various cancers and consumption of animal products. Get a load of this new study, apparently meat raises lung cancer risk. Maggie Fox of Reuters reports:

People who eat a lot of red meat and processed meats have a higher risk of several types of cancer, including lung cancer and colorectal cancer, U.S. researchers reported on Monday.


The work is the first big study to show a link between meat and lung cancer. It also shows that people who eat a lot of meat have a higher risk of liver and esophageal cancer and that men raise their risk of pancreatic cancer by eating red meat.

"A decrease in the consumption of red and processed meat could reduce the incidence of cancer at multiple sites," Dr. Amanda Cross and colleagues at the U.S. National Cancer Institute wrote in their report, published in the Public Library of Science journal PLoS Medicine.

Aren’t you happy you avoid red meat? In the end, I guess it’s important to remember, that while you don’t necessarily have to be vegan or vegetarian, according to Dr. Fuhrman, its best to limit how much meat you eat. One more quote:

Today the link between animal products and many different diseases is as strongly supporting in the scientific literature as the link between cigarette smoking and lung cancer. For example, subjects who ate meat, including poultry and fish, were found to be twice as likely to develop dementia (loss of intellectual function with aging) than their vegetarian counterparts in a carefully designed study.4 The discrepancy was further widened when past meat consumption was taken into account. The same diet, loaded with animal products, that causes heart disease and cancer also causes most every other disease prevalent in America including kidney stones, renal insufficiency and renal failure, osteoporosis, uterine fibroids, hypertension, appendicitis, diverticulosis, and thrombosis.5

So, when people ask you if you miss the proverbial standard American double-cheese burger, you shouldn’t have to fake a sigh and pretend that you do—I don’t!

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Friday: Health Points

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In just under 2 percent of these patients, the mild knee arthritis was accompanied by non-small cell lung cancer. All patients were middle-aged men who had been heavy smokers for most of their lives. Once the cancer tissue was surgically removed, the knee pain cleared up as well.

About 85 percent of all lung cancers are non-small cell lung cancer, according to the American Cancer Society. Unless it is caught early, non-small cell lung cancer is difficult to treat. It spreads to the bones in one in five cases and is well advanced by the time it is diagnosed in half of all cases.

Mmm mmm, this is about as easy a freebie you'll ever see and I encourage you to take advantage of it before 11:59pm on September 29, 2007. But don't wait until the last minute because only one million of these coupons will be distributed and then they are gone…


…Easy peasy and it's FREE FOOD! If you ask for the chicken to be chargrilled without the bun, then they'll give you plenty of greens to wrap it in. And the Diet Coke can be replaced with unsweetened tea if you'd like that better.

After the salmonella strain, Salmonella Schwarzengrund, was detected in two dogs in the homes of two of the ill persons, and in unopened bags of dog food produced by Mars Petcare in the Everson plant in Fayette County, the company voluntarily recalled two brands Aug. 21. The plant was closed last week for inspection and cleaning. Officials from the company could not be reached to update the plant's status.


Further investigation of the outbreak is a collaboration between the U.S. Centers for Disease Control and Prevention, health officials in the affected states and the U.S. Food and Drug Administration.

The break in the case -- tracing human sickness to dog food -- was made by Pennsylvania investigators, led by Dr. Stephen Ostroff, director of the bureau of epidemiology at the state Health Department.

San Francisco's Mayor Newsom, is supporting better nutrition options at schools with a $500,000 grant to the SFUSD Student Nutrition Services (SNS). What will be done with the money? SNS is planning to install salad bars at 25 SF schools this year, including three schools with Urban Sprouts gardens: June Jordan School for Equity, Excelsior Middle School and Martin Luther King, Jr. Middle School.

Researchers for the first time used the National Cancer Data Base, a tumor registry maintained by the American College of Surgeons, to explore these issues, using more than 170,000 cases diagnosed in 1998. Ten percent were in black women.

The study focused on the 95,500 women whose cancers were invasive rather than still confined to a milk duct. About 39 percent of such tumors in black women were estrogen receptor-negative, or ER-negative, compared with 22 percent of those in white women.

Estrogen helps tumors grow. Drugs that block this hormone, like tamoxifen and a newer class of medications called aromatase inhibitors, work against these cancers.

This characterization of the 1918 pandemic virus (serotype H1N1) as "swine flu" came back to haunt us in 1976, when H1N1 caused the death of a solider at Fort Dix, New Jersey and triggered a mass vaccination campaign here in the U.S. (with its subsequent fallout). Since then, sporadic human cases of swine influenza have been reported, either clincally (such as this one in Iowa earlier this year, or subclinically, as described in this research. Now in Ohio, they're looking to see whether swine flu has again jumped into humans. More after the jump.

After analyzing a year’s worth of sales data, Hannaford found that customers tended to buy leaner cuts of meat. Sales of ground beef with stars on their labels increased 7 percent, and sales of chicken that had a star rating rose 5 percent. Sales of ground beef labeled with no stars dropped by 5 percent, while sales of chicken that had a zero-star rating declined 3 percent.


Similarly, sales of whole milk, which received no stars, declined by 4 percent, while sales of fat-free milk (three stars) increased 1 percent.

Sales of fruits and vegetables, however, remained about the same as they did before the ratings were introduced. All fresh produce received stars.

The frequency of hot flashes among the women decreased 50 percent over six weeks. Flaxseed contains lignans and omega-3 fatty acids. Lignans have weak estrogen characteristics. Dr. Pruthi cautions that this was a pilot study and further study in a large, randomized placebo-controlled study may not turn out such results.

  • Not sure what to say about this one, but, get a load—a big load—of China’s newest pop-stars. Brace yourself. Maureen Fan of The Washington Post reports:

On stage, however, the four members of a singing group known as Qian Jin Zu He are strong and confident, belting out their signature rap song, "So What If I'm Fat," passing out photographs of themselves and signing autographs.


The lead singer, 26-year-old Xiao Yang, is 375 pounds; the others in the group are between about 200 and 300 pounds. Together, they tour the country, performing at nightclubs, paint factories, garment industry conventions and shopping malls.

Their success has been modest, but given the powerful discrimination against the obese in China, Xiao said her discovery by a talent agent has been "like a tree branch saving me in the water."

Powerful Flax

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The Cancer Blog knows flaxseed is one heck of a super food. Take a look:

Flax, also known as Common Flax or Linseed, is an annual plant that grows to 120 cm tall, with slender stems. Native to the region extending from the eastern Mediterranean to India, its leaves are green, its flowers blue, its fruit round and containing glossy brown seeds. Grown for both its seeds and its fibers, parts of this plant are used to make fabric, dye, paper, medicines, fishing nets, and soap. The seeds, like what sit in my refrigerator, come in two forms -- brown and yellow or golden. The yellow, golden variety is the one most often consumed.


Consumption of flax seed is good for several reasons, thanks to lignans that power it with nutrition. It contains beneficial levels of omega-3 fatty acids, promotes heart health, lessons the severity of diabetes, and has anti-cancer properties. A series of research studies at the University of Toronto have shown that flaxseed can reduce tumor growth in mice, particularly the tumors found in human post-menopausal breast cancer.

Dr. Fuhrman’s down with flax too. From Disease-Proof Your Child:

Flax seeds are rich in lignans and omega-3 fatty acids, and scientific studies have confirmed that flax seeds have a positive influence on everything from cholesterol levels and constipation to cancer and heart disease. Use ground flax seed in oatmeal, or add them to whipped frozen bananas, stewed apples, and cinnamon and nut balls. Keep in mind that the scientifically documented benefits from flax seeds come from raw, ground flax seed, not flax seed oil.

Cancer: No Shark for You!

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Shark cartilage is being used to treat cancer? Who prescribes that, a witch doctor? “Take two eye of newt and a shark fin and call me in da’ mornin’ mon.” But unfortunately for witch doctors and shaman, a new study shows shark cartilage is no help against lung cancer. Maggie Fox of Reuters reports:

Shark cartilage products have been marketed for years as "alternative" products by several firms, and one Canadian company, Aeterna Zentaris Inc., had been developing one such product as a licensed pharmaceutical.


But the large study, sponsored by the National Cancer Institute, showed definitively that the product did not work, experts told a meeting of the American Society of Clinical Oncology in Chicago…

… The study fits in with several others that have been published in recent years showing that various shark cartilage products do not help cancer patients live any longer, or help ease their symptoms.

"I would like to hope, I would like to pray, that this would put this sort of therapy out of business," Dr. Nancy Davidson, an oncologist at Johns Hopkins University in Baltimore who is about to become president of the American Society of Clinical Oncology, said in an interview.

Don’t worry. You won’t find Dr. Fuhrman consulting the stones and bones for magic remedies. He’s doesn’t believe the hype surrounding shark cartilage on bit. From Ineffective Anti-Cancer Remedies: Shark Cartilage:

This is a perfect example of how a good story can sprout a billion dollar industry. After the book Sharks Don't Get Cancer aired on television, showing cancer patients using shark cartilage apparently doing well, millions of cancer sufferers took (expensive) shark cartilage for years, until the first well-designed study followed cancer patients over time and found the shark cartilage had no discernible effect. Since then, manufacturers have stopped claiming that shark cartilage has any beneficial anti-cancer properties.

Why do I hear the Jaws theme song all of a sudden? Ah!

Fruits and Veggies Beat Up Lung Disease Risk

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Surprise-surprise, a diet rich in fruits and veggies helps prevent lung disease. Let’s hear it, a big collective—duh! Even though we all know it, it’s still worth a read. Steven Reinberg of HealthDay News reports:

People who follow a "Mediterranean" diet rich in fruit, vegetables, whole grains and fish cut their risk of developing chronic obstructive pulmonary disease (COPD) by half, researchers report.

COPD, a lethal combination of emphysema and bronchitis, is expected to become the third leading cause of death worldwide by 2020.

Smoking remains the primary cause of COPD, according to the report in the May 14 online edition of the journal Thorax.

Therefore, "The first message is that people have to stop smoking," said lead researcher Dr. Raphaelle Varraso, from INSERM, Villejuif, France. "And then, that a diet rich in fruits, vegetables and fish may help to reduce risk of COPD."

And, if healthy food can cut the odds for COPD, unhealthy eating could do the opposite, he said. "In smokers and ex-smokers, a diet rich in refined grains, cured and red meats, desserts and French fries may increase the risk of COPD," Varraso said.

His group collected data on almost 43,000 men who took part in the U.S. Health Professionals Follow-up Study, which started in 1986. The study included more than 50,000 U.S. health care professionals ages 40 to 75.

Every two years, the men were asked about their lifestyle, including smoking and exercise, diet and medical history. Detailed diet information was gathered every four years.

Diet, Chemotherapy, and the Truth: How to Win the War on Cancer

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We live in an era where the majority of Americans think that diseases strike us because of either misfortune, genetics, or unknown factors beyond our control. When serious disease "strikes," we run to doctors and expect them to fix us with a pill. Most people have no idea that most diseases--including cancers, heart disease, strokes, and diabetes--are the result of nutritional folly. Because they do not know that adults lived much longer centuries ago, they accept the myth that we are living healthier and longer today.

If we were taught from childhood that the diseases we suffer in the modern world are the tragic consequence of our toxic food environment, we wouldn't be in today's disgraceful situation--where people graduate from high school, college, and even graduate school without learning how to protect, preserve, and restore their precious health. With proper health education, we would learn that our bodies are powerfully resistant to disease when nutritional needs are met. Instead, we have become the victims of the high-tech, mass-produced food culture that is fueling a cancer epidemic unrivaled in human history.

Chemotherapy Mentality
Our technologically-advanced society is suffering from the highest rates of cancer ever seen in human history, rates that are also much higher than in less developed parts of the world. Since 1999, cancer has surpassed heart disease and has become the leading cause of age adjusted mortality for Americans younger than 85. Despite more than a hundred billion dollars in cancer research-- invested largely in the development of drug chemotherapy and screening and detection techniques--we have lost the war on cancer. While there has been a slight reduction of cancer-related deaths in the last 25 years, this is largely the result of the decrease in lung cancer deaths that has resulted from a reduction in cigarette smoking during this timeframe. Mortality rates for most cancers have stayed remarkably steady.

Chemotherapy has contributed to the progress made against cancer deaths from fast-growing cancers, such as leukemia, lymphoma, testicular cancer, and childhood cancers such as osteogenic sarcoma. But for the major cancers affecting most adult Americans, chemotherapy adds less than one year of disease-free life to those treated.

Science or Profits?
At present, pharmaceutical companies-- not independent medical or scientific researchers--control the vast majority of research and clinical trials. We have lost the judgment and rationale of independent experts and now depend on drug companies to honestly report the risks and benefits of drugs they manufacture and sell. This is like asking the fast-food industry to be in charge of our nutritional advice. The medical studies that drug companies pay for and publicize are heavily biased in favor of the drugs they sell. The economically powerful pharmaceutical industry and the large chemical-food conglomerates wield undue influence on government and the media. Accurate nutritional information is rarely reported because the media cannot produce stories that go against the interests of their advertisers. Instead, the media is quick to report on drug company press releases--self-serving propaganda announcing new anticancer "breakthroughs" that reinforce the myth that we are winning the war against cancer.

Mythical Breakthroughs
Most often, the so-called "benefits" described by drug companies announce improved "response rates," for example, when tumor burden is lessened. But an improved response rate means little if the patient does not survive longer. And even the cancer industry's meager definition of survival--living 5 years beyond diagnosis--can be misleading. If "advances" in chemotherapy result in a higher percentage of people surviving for 5 years than did previously, that can be reported as "progress." But if most of them still die between years 5 and 10, it hardly can be called a big success, especially if the same number or more people would have survived 10 years or longer without the chemotherapy.

Unless overall survival and quality of life are improved, it matters not if chemotherapy resulted in tumor shrinkage, or if a slight increase is seen in 5-year survival statistics. By using virtually meaningless terms like "response rates" and "disease-free survival," researchers can report results that make chemotherapy look more effective than it really is.

Unless patients do some investigating of their own, they have no way of knowing that the glowingly optimistic results reported in the press--and too often parroted by their doctors--are designed to lead them to chemotherapy even though it is a poor choice for both quality and duration of life. The false perception that chemotherapy offers significant life-span benefits for cancer sufferers is dramatically juxtaposed by the fact that so many more people die of cancer today than they did years ago. In fact, a Swedish study showed that the risk of developing cancer and dying of it was three times higher in people born in the 1950s compared with those born in the 1880s. Since 1958, cancer has increased 55 percent in men and only slightly less in women.1

Does Chemotherapy Work?
Let's see how effective chemotherapy actually is with a few common cancers.

  • A meta-analysis of chemotherapy for postmenopausal, estrogen receptor-positive women (the largest group of women with breast cancer) pooled the six largest studies to get the most accurate data on survival and complications. Here is what researchers concluded about the group treated with standard chemotherapy: "No significant survival benefit was observed."2
  • In non-small cell lung cancer (the most common type), the 5- year survival is only about 10 percent. In stage 4, when the cancer has spread to distant sites, the 5-year survival is only 1.6 percent. After looking at multiple studies, it appears that treatment generally results in a very slight improved survival rate at 1 year, but this advantage disappeared at 30 months of follow- up.3
  • Even in small cell lung cancer where chemotherapy has proven effectiveness in life extension, the benefit adds only a few months of life, not years. And during this time the patient can experience serious--even life threatening-- side effects from the treatment.

What Should You Do?
If you have cancer and are considering chemotherapy, it is wise to do a search on all of the studies done on the recommended therapy (using med-line, for instance), so an informed decision can be made. If this were done, most patients likely would refuse chemotherapy. Doctors generally hide and distort the realities of chemotherapy, talking to patients about "shrinking the cancer" and "killing cancer cells," not mentioning the fact that the therapy has not been shown to extend life.

Every patient has to make her own decision. But if I were a woman with postmenopausal breast cancer, I would opt for surgery, without radiation and without chemotherapy, and would then pursue an aggressive nutritional protocol. I also would include antiestrogens if the tumor histology showed it to be estrogen receptor- positive.

War Against Good Nutrition
While the "war against cancer" is being fought with the wet noodle of chemotherapy, we are observing a significant increase in some cancers, such as malignant melanoma, multiple myeloma, and prostate cancer. Our population is heavier and as cancer-prone as ever. While we are pouring billions of dollars into drug companies and cancer centers, millions of people continue to die from what should be a preventable disease.

Almost nothing has been done to teach people about the power of nutritional excellence to protect against cancer. In fact, the media regularly reports that nutrition does not affect cancer. For example, a recent New York Times (G. Kolata, September 27,2005,"Science Times") article reported that diet had only a "hypothetical" relationship with cancer. This ludicrous pronouncement was based on studies that showed that perimenopausal women who eat less fat still have high cancer rates. The Times evidently does not understand that modestly reducing fat and eating more chicken and pasta is not an anti-cancer program.

We are losing the war on cancer, and our government policies are actually worsening the problem. With all of the recent advances in science pointing to phytonutrient deficiency as the major cause of cancer, our efforts should focus on prevention; educating the public about proper diet and nutrition. Millions of lives can be saved. We also can eliminate the tragic consequences and family trauma of living with cancer---diagnoses, surgeries, radiation, chemotherapies, suffering, and premature death, which come from the cancer and very often from the treatment.

Avoiding Cancer
Your body is a self-repairing and self-healing machine. Human cells have all the features necessary to protect themselves from chemical damage to their DNA that eventually results in carcinogenic changes. A cancer cell is essentially a normal cell whose DNA has been damaged to the point that it can no longer control its replication. The process that is creating our modern epidemic of cancer is twofold. One aspect involves the exposure of our cells to damaging stresses such as chemical carcinogens, radon, acrylamides, and high levels of saturated and trans fats and animal protein. At the same time, we have a woefully insufficient dietary intake of plant-derived nutrients, which renders our cells incapable of functioning to their fullest potential for repair and maintenance.

Our cells have built-in, powerful mechanisms to remove or destroy toxic substances, inhibit DNA damage, repair broken DNA cross-links, and remove cells that are injured or abnormal before they become cancerous. In recent years, the term phytochemicals has been used to refer to the thousands of newly-discovered nutrients supplied by plants that---in addition to vitamins and minerals---are necessary for maximal immune system protection and for the promotion of cellular detoxification and repair.

Most of our knowledge about what constitutes the optimal cancer prevention diet comes from both human population (epidemiological) studies and animal studies. Populations that have a high intake of natural, unrefined plant foods such as fruits, vegetables, seeds, nuts, and beans always have a low incidence of cancer, proportional to the intake of these phytochemcal-rich plant foods.

Even though other factors such as chemicals, pollution, and smoking play a role in cancer etiology, the scientific literature still illustrates that a better diet offers dramatic protection even against nondietary cancer promoters. For example, the Fiji Islands (where smoking rates are high) still has a dramatically lower incidence of lung cancer than Hawaii (where smoking rates are lower). This protection against lung cancer even in heavily smoking Fiji Islanders was shown to be the result of the high intake of green vegetables in Fiji.4

Examining data from numerous epidemiological studies, the World Cancer Research Fund concluded that the evidence that fruits and vegetables may reduce the risk of oral, esophageal, lung, stomach, colon, pancreatic, bladder, and breast cancer was convincing. No single substance in a plant-based diet accounts for this relationship; rather, it is the synergistic effect of multiple phytochemical compounds (which number in the thousands).

The National Cancer Institute recommends eating 5 servings of fruits and vegetables each day. However, scientific studies suggest that more is better and that much, much more is much, much better at reducing cancer risk. It is a national disgrace that very few Americans follow this very minimal recommendation to eat 5 servings of fruits and vegetables daily.

Cruciferous Vegetables
While fruits and vegetables are excellent sources of nutrients, the consumption of vegetables is more helpful in reducing cancer because they contain much higher amounts of cancer-protective compounds-- especially green vegetables. Among these green vegetables, the cruciferous family has demonstrated the most dramatic protection against cancer. Cruciferous vegetables (broccoli, brussels sprouts, cauliflower, kale, bok choy, collards, arugala, watercress, and cabbage) contain a symphony of phytonutrients with potent anti-cancer effects. Isothiocyanates (ITCs), which are perhaps the best studied, have been shown to provide protection against environmental carcinogen exposure by inducing detoxification pathways, thereby neutralizing potential carcinogens.

These vegetables also contain indole-3- carbinol (I3C). Indole-3-carbinol has been shown to reduce the risk of breast cancer by decreasing estrogen activity. Important recent studies have shown that cruciferous vegetables and the compounds they contain can do the following:


  • halt the growth of breast cancer cells;5
  • dramatically reduce the risk of colon cancer;6
  • prevent the replication of prostate cancer cells and induce death of cancerous cells;7
  • inhibit the progression of lung cancer.8


What makes these studies even more fascinating is the discovery of the gene/diet interaction, which has shown that high intake of greens and cruciferous vegetables provides the food factors necessary to interact with--and prevent-- genetic defects from creating disease. This gene/diet interaction activates a battery of many genes, initiating DNA repair and other protection mechanisms.

These cellular repair and detoxification mechanisms are most powerfully induced by eating a mixture of both raw and cooked cruciferous plant foods. Some of the compounds are water soluble and heat stable, and absorption is increased when cooked, for example, in a soup. Other critical ITCs are heat sensitive and are better transmitted in the raw form.

Carotenoids & Polyphenols
Population studies show an association between high dietary intake of carotenoid-containing fruits and vegetables and reduced risk of prostate, breast, and head and neck cancers. A high dietary intake of fruits and vegetables provides a spectrum of carotenoids, including alphacarotene, gamma-carotene, betacryptoxanthin, zeaxanthin, lutein, and lycopene.

Vegetable juices (carrot, tomato, spinach, and other greens) represent a particularly potent form of carotenoids. Scientists have demonstrated that drinking carrot juice significantly reduces free radical damage to genes. Tomato juice and cooked tomatoes rich in lycopene and other potent antioxidants help reduce the oxidation of the "bad" LDL cholesterol and also have been shown to dramatically help protect against cancer. Carotenoid-rich extracts of carrots and tomatoes have been shown to substantially inhibit the early stages of liver cancer in animals.

Fruits also contain various key phytochemicals. For example, resveratrol, found in grapes, has been reported to exert a variety of anticancer effects. Studies have demonstrated that resveratrol causes growth inhibition of human colon and breast cancer cells. Ellagic acid, found in strawberries, grapes, blueberries, raspberries, and blackberries, is another polyphenol that has demonstrated anticarcinogenic potential in animal studies.

This article is from the Healthy Times newsletter, a complete archive of which is available to members of DrFuhrman.com.

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"A Symphony of Phytonutrients" from Cruciferous Vegetables

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While fruits and vegetables are excellent sources of nutrients, the consumption of vegetables is more helpful in reducing cancer because they contain much higher amounts of cancer-protective compounds--especially green vegetables. Among these green vegetables, the cruciferous family has demonstrated the most dramatic protection against cancer. Cruciferous vegetables (broccoli, brussels sprouts, cauliflower, kale, bok choy, collards, arugala, watercress, and cabbage) contain a symphony of phytonutrients with potent anti-cancer effects.

Isothiocyanates (ITCs), which are perhaps the best studied, have been shown to provide protection against environmental carcinogen exposure by inducing detoxification pathways, thereby neutralizing potential carcinogens. These vegetables also contain indole-3-carbinol (I3C). Indole-3-carbinol has been shown to reduce the risk of breast cancer by decreasing estrogen activity.

Important recent studies have shown that cruciferous vegetables
and the compounds they contain can do the following:

* halt the growth of breast cancer cells1
* dramatically reduce the risk of colon cancer2
* prevent the replication of prostate cancer cells and induce death of cancerous cells3
* inhibit the progression of lung cancer4

What makes these studies even more fascinating is the discovery of the gene/diet interaction, which has shown that high intake of greens and cruciferous vegetables provides the food factors necessary to interact with--and prevent--genetic defects from creating disease. This gene/diet interaction activates a battery of many genes, initiating DNA repair and other protection mechanisms.

These cellular repair and detoxification mechanisms are most powerfully induced by eating a mixture of both raw and cooked cruciferous plant foods. Some of the compounds are water soluble and heat stable, and absorption is increased when cooked, for example, in a soup. Other critical ITCs are heat sensitive and are better transmitted in the raw form.

Continue Reading

The Lancet: Cruciferous Vegetables Protect Against Lung Cancer

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It's a great day: the big photo at the moment on the website of the medical journal The Lancet is of some of Dr. Fuhrman's favorite medicines: cabbage, kale, Brussels sprouts, broccoli, and all those cruciferous vegetables that are so good for you.

The caption explains the results of an important new study:

Eating vegetables from the cabbage family could help individuals with a certain genetic make-up reduce their risk of lung cancer. Weekly consumption of cruciferous vegetables had a 72% protective effect against lung cancer in people who had inactive forms of both the GSTM1 and GSTT1 genes.

If you read the whole abstract, you will find this summation:

These data provide strong evidence for a substantial protective effect of cruciferous vegetable consumption on lung cancer.

Observational studies have provided consistent evidence for a protective role of vegetable consumption against lung cancer, with the evidence being most apparent for green cruciferous vegetables such as broccoli and cabbage. Such vegetables are rich in isothiocyanates, which have been shown in animals to have strong chemopreventative properties against lung cancer.


The article is by Paul Brennan, Charles C Hsu, Norman Moullan, Neonilia Szeszenia-Dabrowska , Jolanta Lissowska, David Zaridze, Peter Rudnai, Eleonora Fabianova, Dana Mates, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Federica Gemignani, Amelie Chabrier, Janet Hall, Rayjean J Hung, Paolo Boffetta, and Federico Canzian.

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