Onward Phytochemicals, Onward!

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There are lots of ways you can improve your health; eat better, exercise, getting plenty of rest, but what’s the best thing you can do? Dr. Fuhrman tells us:

The most powerful thing you can do to improve your health is to eat more green vegetables. Americans eat a piddling amount of greens. If they ate a lot more, disease rates of all types would plummet. Not only are vegetables rich in vitamins and minerals, they also contain thousands of phytochemicals that are critically important for our health.

For real, green vegetables are strong mojo and—quite frankly—green vegetables are nutritional rock stars. Just look at them:



Now, back to the phytochemicals. Stan Kent from Healthy Eating loves phytonutrients! From his post, Phytonutrients Are The New Direction For Healing:

Phytonutrients in vegetables are probably the best hope for stopping some of the most deadly and stubborn diseases.(Newsweek magazine). I have witnessed that as well. These remarkable compounds have nothing in common with the vitamins, supplements and so-called "natural" products sold in health stores, drug stores or on the internet. Most ordinary supplements and vitamins, like pharmaceuticals are totally synthetic. Isolating chemicals is not the same as the combination provided by nature in the foods we eat. What are Phytonutrients?


Phytonutrients are therapeutic foods that are grown, harvested and properly produced without heat. They are a complex combination of plant-based phytochemicals, enzymes, vitamins and minerals. My "Nutrition-Based-Regimen" is based on the herbs vitamins and minerals - what they do for you and what foods to eat to get them. The practice of using phytonutrients to heal may be on the cutting edge of medical science.

Dr. Fuhrman would agree. Phytonutrients and phytochemicals are the next great discovery in health. He talks about it:

We are on the verge of a revolution. Substances newly discovered in broccoli cabbage sprouts sweep toxins out of cells. Substances found in nuts and beans prevent damage to our cells' DNA. Other compounds in beets, peppers, and tomatoes fight cancerous changes in cells. Oranges and apples protect our blood vessels from damage that could lead to heart disease. Nature's chemoprotective army is alert and ready to remove our enemies and shield us from harm.


Hardly a day goes by when some new study doesn't proclaim the health-giving properties of fruits, vegetables, and beans. Unprocessed plant foods contain thousands of compounds, most of which have not yet been discovered, that are essential for maintaining health and maximizing genetic potential. Welcome to the phytochemical revolution.

Here is just a short list of the amazing things plant nutrients can do for you. Check it out:

  • Halt the growth of breast cancer cells, 1
  • Dramatically reduce the risk of colon cancer, 2
  • Prevent the replication of prostate cancer cells and induce death of cancerous cells, 3
  • Inhibit the progression of lung cancer, 4
Okay, I’m pumped up—WHERE’S MY BROCCOLI!

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Heart Health: Bad News, Good News, Stupid News...

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Quick, panic! A new study claims that people with diabetes have the same heart attack risk as individuals who have already had a heart attack. Reuters reports:

The finding, which appears in the American Heart Association's journal Circulation, comes from a study of 3.3 million residents of Denmark who were at least 30 years of age. Overall, 2.2 percent of subjects had diabetes and 2.4 percent had a prior heart attack.


Dr. Tina Ken Schramm and colleagues found that, compared with men without diabetes or a prior heart attack, those with diabetes were 2.32-times more likely to experience a stroke, heart attack or death from cardiovascular causes, and those with a prior heart attack were 2.48-times more likely.

For women, the corresponding risks were raised 2.48- and 2.71-times.

You’ve got to do something! How about exercise? New research suggests that modest exercise can fight heart disease. More from the AFP:

French doctors on Tuesday said that an overview of the latest research into sport and good health proved that moderate, frequent exercise combated the risk of heart disease, diabetes, colon cancer, respiratory disease and depression.


The report by the National Institute for Health and Medical Research (Inserm) sets a benchmark, for adults, of at least 30 minutes of modest exercise, such as fast walking, at least five times a week, or 20 minutes of harder exercise, such as jogging, three times a week.

Young people are advised to do twice this regime to maintain fitness.

Good, but if you like bike riding. You might want to stay away from The Stupidest Bike Lane in America. Well passes it along:


Now, just in case you haven’t had enough stupid yet. Check out these Weight Loss Sunglasses. No, I’m not joking. Diet Blog is all over it:

This snazzy creation is designed to give food a blue tinge - theoretically rendering food dull and unpalatable. Kind of the opposite phenomenon of "beer goggles"?


While your first instinct may be to snicker (as it should be), there is actual physiological and psychological rationale to this theory: Certain colours tend to stimulate appetite, while others tend to deter it. Apparently, blue is considered to be the least appetizing color of the spectrum, with red and yellow being at the opposite end as a hunger stimulant.

Well George Carlin said it best, in life, there’re a few winners, and a whole-lot of losers. Short bike lanes and magic sunglasses—LOSERS!

Friday: Health Points

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The FDA is in charge of 80 percent of the U.S. food supply, mostly fruits and vegetables, and has been criticized as being too passive in handling the growing surge of imports into the United States. Total imports, including food, total $2 trillion annually.

"FDA has failed to implement literally hundreds of proposed solutions to specific import problems, which would have enabled the FDA to begin to progressively focus its limited resources where the risks are indeed the greatest," said Benjamin England, a former FDA official who co-founded a consulting firm that helps foreign and U.S. companies meet FDA import rules.

  • Are you a runner? If you are, you might want to consider running with a group. It’s a lot more fun. Gina Kolata of The New York Times explains:

Those who run in packs are part of a select society, or maybe a self-selected society. Anyone can join, but you have to run and you have to go to the designated meeting place at the designated time. You might join a club that sponsors runs each week or you might go to a place like a parking lot behind a school where runners gather on weekend mornings. It’s not hard to find these meeting places; local running groups and running stores know where to go. And when you show up, ready to run, the society opens up to you.


For the most part, these groups are not made up of people who are jogging for their health or because they want to lose weight. They are made up mostly of people who have been running long enough to be able to continue for miles and miles. And they love it. They are running for the sheer joy of it and for company to push them to run longer and faster and to share the inevitable pain that comes with the effort to improve.

People newly diagnosed with coronary artery disease had nearly double the normal incidence of colorectal tumors and cancers, a study by Hong Kong researchers found.


Both the tumors and the heart disease "probably develop through the mechanism of chronic inflammation," said the report by researchers at the University of Hong Kong that's published in the Sept. 26 issue of the Journal of the American Medical Association.

"Liquid candy" to detractors, sweetened soft drinks are so ubiquitous that they contribute about 10 percent of the calories in the American diet, according to government data.


In fact, said Dr. David Ludwig, a Harvard endocrinologist whose 2001 paper in the Lancet is widely cited by obesity researchers, sweetened drinks are the only specific food that clinical research has directly linked to weight gain.

"Highly concentrated starches and sugars promote overeating, and the granddaddy of them all is sugar-sweetened beverages," said Ludwig, who runs the Optimal Weight for Life Program at Children's Hospital in Boston.

  1. Get your food and go - Many work and social functions involve a large table covered with tasty looking morsels. Don't be one of those people who stand next to the table. Get your plate, put your food on it, and leave the table. Period.
  2. Choose a small plate Seems obvious - But a large plate typically means lots of food and all hope of appropriate portion size is abandoned

Health Canada is aware of the growing body of evidence on the role of vitamin D in relation to health. While a number of independent recommendations concerning vitamin D intake have been issued by various organizations, Health Canada believes these recommendations are premature and that a comprehensive review that looks at both benefits and safety needs to be undertaken before the Department can issue a revised recommendation.

Erectile dysfunction is the consistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. In a study of 4,763 Chinese men aged 35 to 74 years who were free of blood vessel disease and who reported that they had been sexually active within the last 6 months, the researchers found a significant statistical link between the number of cigarettes smoked and the likelihood of erectile dysfunction.


"The association between cigarette smoking and erectile dysfunction was found in earlier studies," said first author Dr. Jiang He of Tulane University School of Public Health, New Orleans. "However, most of those studies were conducted in patients with hypertension (high blood pressure), diabetes and cardiovascular disease. What distinguishes this study is that it is the first to find this association among healthy men."

  • Reduces risk of injury by strengthening muscles and joints.
  • Increases and restores bone density, helping prevent osteoporosis.
  • Builds lean muscle tissue, which burns more calories than fat.

Cruciferous Phytochemicals at Work

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From the July 2007 edition of Dr. Fuhrman's Healthy Times:

Cruciferous vegetables contain phytochemicals that have unique abilities to modify human hormones, detoxify compounds, and prevent toxic compounds from binding to human DNA, preventing toxins from causing DNA damage that could lead to cancer.

Cruciferous vegetables are unique in that they are rich sources of sulfur-containing compounds known as glucosinolates. It is the presence of glucosinolates that makes a vegetable earn the designation of cruciferous. There have been over 120 glucosinolates identified. These compounds help produce other healthful compounds, which is important since humans do not absorb glucosinolates well.

Myrosinase is an enzyme that is compartmentalized (separated) in the cell walls of cruciferous vegetables. It is released only when the cell walls are damaged (for example, via chewing, chopping, blending, or juicing), at which point it catalyzes the conversion of glucosinolates into isothiocyanates (ITCs) such as indole 3-carbonole. These ITCs are well absorbed and have potent and diverse beneficial effects in humans and other animals.

Myrosinase is deactivated by cooking. The more the food is heated, the more is lost. As a result, fewer isothiocyanates are produced when we cook and overcook these vegetables. Maximum levels of these highly potent anticancer compounds are available from raw vegetables that are somewhat bitter, such as broccoli sprouts, watercress, and arugula.The very high levels of isothiocyanates (ITCs) produced by these foods give that “bitter” taste. However, myrosinase also is produced by the gut flora, so absorption of compounds derived from cruciferous vegetables is still possible from cooked greens.

Sulforaphane, broccoli’s much studied compound, is an isothiocyanate that has a unique mechanism of action. This compound blocks chemical-initiated tumor formation and induces cell cycle arrest in abnormal cells, meaning that it inhibits growth and induces cell death in cells with early cancerous changes in a dose-dependent manner (i.e., the more you eat, the better). Recent studies show that the amount of sulforaphane derived from eating a reasonable amount of broccoli can have dramatic effects to protect against colon cancer.

Dark Vegetables

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No, that’s not the name of a horror movie. Rather, some really great veggies that’ll help you ward off disease. The Cancer Blog investigates new research that claims dark fruits and vegetables help fight colon cancer. Take a look:

I'm of the mind that blueberries harness one of the best arsenals of natural cancer-fighting nutrition known to the planet, so it's good to see a new study reiterate this fact. Ever try fresh blueberries on top of 100% whole-grain waffles? Makes an excellent breakfast, while at the same time giving your body a shower of anti-cancer nutrition.


Evidence has shown in the past that anthocyanins (the dark color compounds in some fruits and veggies) can slow the growth of colon cancer cells by 50 to 80 percent. This just in -- they taste fantastic as well.

Here are a couple more dark-powerhouses. From Ten Super Foods to Use in Your Recipes and Menus:

Blueberries/Blackberries are packed with tannins, anthocyanidins, flavonoids, polyphenols, and proanthcyanidins that have been linked to prevention and reversal of age-related mental decline. They also have powerful anti-cancer effects. Use frozen organic berries in the winter when fresh ones are not available.


Carrots/Beets are colorful root crops that add beauty and flavor to dishes. Shredded raw in salads, cooked, or in soups, they are high in fiber and antioxidants compounds such as cartonoids abd betacyanin, a powerful cancer protective agent found to inhibit cell mutations.

Powerful Flax

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The Cancer Blog knows flaxseed is one heck of a super food. Take a look:

Flax, also known as Common Flax or Linseed, is an annual plant that grows to 120 cm tall, with slender stems. Native to the region extending from the eastern Mediterranean to India, its leaves are green, its flowers blue, its fruit round and containing glossy brown seeds. Grown for both its seeds and its fibers, parts of this plant are used to make fabric, dye, paper, medicines, fishing nets, and soap. The seeds, like what sit in my refrigerator, come in two forms -- brown and yellow or golden. The yellow, golden variety is the one most often consumed.


Consumption of flax seed is good for several reasons, thanks to lignans that power it with nutrition. It contains beneficial levels of omega-3 fatty acids, promotes heart health, lessons the severity of diabetes, and has anti-cancer properties. A series of research studies at the University of Toronto have shown that flaxseed can reduce tumor growth in mice, particularly the tumors found in human post-menopausal breast cancer.

Dr. Fuhrman’s down with flax too. From Disease-Proof Your Child:

Flax seeds are rich in lignans and omega-3 fatty acids, and scientific studies have confirmed that flax seeds have a positive influence on everything from cholesterol levels and constipation to cancer and heart disease. Use ground flax seed in oatmeal, or add them to whipped frozen bananas, stewed apples, and cinnamon and nut balls. Keep in mind that the scientifically documented benefits from flax seeds come from raw, ground flax seed, not flax seed oil.

Cancer: Humans Need Plant Matter

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Adapted from Dr. Fuhrman’s book Eat to Live:

There is still some controversy about which foods cause which cancers and whether certain types of fat are the culprits with certain cancers, but there’s one thing we know for sure; raw vegetables and fresh fruits have powerful anti-cancer agents. Studies have repeatedly shown the correlation between consumption of these foods and a lower incidence of various cancers, including those of the breast, colon, rectum, lung, stomach, prostate, and pancreas.1 This means that your risk of cancer decreases with an increased intake of fruits and vegetables, and the earlier in life you start eating large amounts of these foods, the more protection you get.

Humans are genetically adapted to expect a high intake of natural and unprocessed plant-derived substances. Cancer is a disease of maladaptation. It results primarily from a body’s lacking critical substances found in different types of vegetation, many of which are still undiscovered, that are metabolically necessary for normal protective function. Natural foods unadulterated by man are highly complex—so complex that the exact structure and the majority of compounds they contain are not precisely known. A tomato, for example, contains more than ten thousand different phytochemicals.

It may never be possible to extract the precise symphony of nutrients found in vegetation and place it in a pill. Isolated nutrients extracted from food may never offer the same level of disease-protective effects of whole natural foods, as nature “designed” them. Fruits and vegetables contain a variety of nutrients, which work in subtle synergies, and many of these nutrients cannot be isolated or extracted. Phytochemicals from a variety of plant foods work together to become much more potent at detoxifying carcinogens and protecting against cancer than when taken individually as isolated compounds.

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Aspirin and Colon Cancer

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The Cancer Blog is all over new research discouraging the use of aspirin for colon cancer prevention:

The risk of intestinal bleeding, stroke, kidney failure, and other health problems led the US Preventative Services Task Force to conclude that taking more than 300 milligrams per day of drugs like Motrin, Advil, and Aleve is just too risky to outweigh the potential benefits of preventing cancer. And while taking less than 100 milligrams of such drugs can reduce the risk of heart disease, it does nothing to lower the rate of colon cancer.

Magic Beans

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Beans, you probably don’t spend a lot of time thinking about them, but they’re actually pretty strong medicine. Now I’m no doctor, so I’ll defer to one. In Eat to Live Dr. Fuhrman points out that, among beans’ many other talents, they can decrease a person’s risk of colon cancer and even reproductive cancers. Take a look:

A large recent study examined the eating habits of 32,000 adults for six years and then watched the incidence of cancer for these subjects over the next six years. Those who avoided red meat but at white meat regularly had a more than 300 percent increase in colon cancer incidence.1 The same study showed that eating beans, peas, or lentils, at least twice a week was associated with a 50 percent lower risk than never eating these foods…


..Beans, in general, not just soy, have additional anti-cancer benefits against reproductive cancers, such as breast and prostate cancer.2

Now, I doubt you thought about that when you were singing, “Beans beans a magical fruit, the more you eat, the more you toot.” Want more bean factoids? Vegan Grandma has got a whole bunch of them:

In some Eastern cultures, legumes have been a basic dietary staple for more than 20,000 years. The lima and pinto bean were cultivated for the first time in the very earliest Mexican and Peruvian civilizations more than 5,000 years ago, being popular in both the Aztec and Inca cultures.

Be sure to check out the part of the post where she lists the many different varieties of beans. You’ll see things like Adzuki Beans and Cranberry Beans—I’m getting hungry already!

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Diet, Chemotherapy, and the Truth: How to Win the War on Cancer

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We live in an era where the majority of Americans think that diseases strike us because of either misfortune, genetics, or unknown factors beyond our control. When serious disease "strikes," we run to doctors and expect them to fix us with a pill. Most people have no idea that most diseases--including cancers, heart disease, strokes, and diabetes--are the result of nutritional folly. Because they do not know that adults lived much longer centuries ago, they accept the myth that we are living healthier and longer today.

If we were taught from childhood that the diseases we suffer in the modern world are the tragic consequence of our toxic food environment, we wouldn't be in today's disgraceful situation--where people graduate from high school, college, and even graduate school without learning how to protect, preserve, and restore their precious health. With proper health education, we would learn that our bodies are powerfully resistant to disease when nutritional needs are met. Instead, we have become the victims of the high-tech, mass-produced food culture that is fueling a cancer epidemic unrivaled in human history.

Chemotherapy Mentality
Our technologically-advanced society is suffering from the highest rates of cancer ever seen in human history, rates that are also much higher than in less developed parts of the world. Since 1999, cancer has surpassed heart disease and has become the leading cause of age adjusted mortality for Americans younger than 85. Despite more than a hundred billion dollars in cancer research-- invested largely in the development of drug chemotherapy and screening and detection techniques--we have lost the war on cancer. While there has been a slight reduction of cancer-related deaths in the last 25 years, this is largely the result of the decrease in lung cancer deaths that has resulted from a reduction in cigarette smoking during this timeframe. Mortality rates for most cancers have stayed remarkably steady.

Chemotherapy has contributed to the progress made against cancer deaths from fast-growing cancers, such as leukemia, lymphoma, testicular cancer, and childhood cancers such as osteogenic sarcoma. But for the major cancers affecting most adult Americans, chemotherapy adds less than one year of disease-free life to those treated.

Science or Profits?
At present, pharmaceutical companies-- not independent medical or scientific researchers--control the vast majority of research and clinical trials. We have lost the judgment and rationale of independent experts and now depend on drug companies to honestly report the risks and benefits of drugs they manufacture and sell. This is like asking the fast-food industry to be in charge of our nutritional advice. The medical studies that drug companies pay for and publicize are heavily biased in favor of the drugs they sell. The economically powerful pharmaceutical industry and the large chemical-food conglomerates wield undue influence on government and the media. Accurate nutritional information is rarely reported because the media cannot produce stories that go against the interests of their advertisers. Instead, the media is quick to report on drug company press releases--self-serving propaganda announcing new anticancer "breakthroughs" that reinforce the myth that we are winning the war against cancer.

Mythical Breakthroughs
Most often, the so-called "benefits" described by drug companies announce improved "response rates," for example, when tumor burden is lessened. But an improved response rate means little if the patient does not survive longer. And even the cancer industry's meager definition of survival--living 5 years beyond diagnosis--can be misleading. If "advances" in chemotherapy result in a higher percentage of people surviving for 5 years than did previously, that can be reported as "progress." But if most of them still die between years 5 and 10, it hardly can be called a big success, especially if the same number or more people would have survived 10 years or longer without the chemotherapy.

Unless overall survival and quality of life are improved, it matters not if chemotherapy resulted in tumor shrinkage, or if a slight increase is seen in 5-year survival statistics. By using virtually meaningless terms like "response rates" and "disease-free survival," researchers can report results that make chemotherapy look more effective than it really is.

Unless patients do some investigating of their own, they have no way of knowing that the glowingly optimistic results reported in the press--and too often parroted by their doctors--are designed to lead them to chemotherapy even though it is a poor choice for both quality and duration of life. The false perception that chemotherapy offers significant life-span benefits for cancer sufferers is dramatically juxtaposed by the fact that so many more people die of cancer today than they did years ago. In fact, a Swedish study showed that the risk of developing cancer and dying of it was three times higher in people born in the 1950s compared with those born in the 1880s. Since 1958, cancer has increased 55 percent in men and only slightly less in women.1

Does Chemotherapy Work?
Let's see how effective chemotherapy actually is with a few common cancers.

  • A meta-analysis of chemotherapy for postmenopausal, estrogen receptor-positive women (the largest group of women with breast cancer) pooled the six largest studies to get the most accurate data on survival and complications. Here is what researchers concluded about the group treated with standard chemotherapy: "No significant survival benefit was observed."2
  • In non-small cell lung cancer (the most common type), the 5- year survival is only about 10 percent. In stage 4, when the cancer has spread to distant sites, the 5-year survival is only 1.6 percent. After looking at multiple studies, it appears that treatment generally results in a very slight improved survival rate at 1 year, but this advantage disappeared at 30 months of follow- up.3
  • Even in small cell lung cancer where chemotherapy has proven effectiveness in life extension, the benefit adds only a few months of life, not years. And during this time the patient can experience serious--even life threatening-- side effects from the treatment.

What Should You Do?
If you have cancer and are considering chemotherapy, it is wise to do a search on all of the studies done on the recommended therapy (using med-line, for instance), so an informed decision can be made. If this were done, most patients likely would refuse chemotherapy. Doctors generally hide and distort the realities of chemotherapy, talking to patients about "shrinking the cancer" and "killing cancer cells," not mentioning the fact that the therapy has not been shown to extend life.

Every patient has to make her own decision. But if I were a woman with postmenopausal breast cancer, I would opt for surgery, without radiation and without chemotherapy, and would then pursue an aggressive nutritional protocol. I also would include antiestrogens if the tumor histology showed it to be estrogen receptor- positive.

War Against Good Nutrition
While the "war against cancer" is being fought with the wet noodle of chemotherapy, we are observing a significant increase in some cancers, such as malignant melanoma, multiple myeloma, and prostate cancer. Our population is heavier and as cancer-prone as ever. While we are pouring billions of dollars into drug companies and cancer centers, millions of people continue to die from what should be a preventable disease.

Almost nothing has been done to teach people about the power of nutritional excellence to protect against cancer. In fact, the media regularly reports that nutrition does not affect cancer. For example, a recent New York Times (G. Kolata, September 27,2005,"Science Times") article reported that diet had only a "hypothetical" relationship with cancer. This ludicrous pronouncement was based on studies that showed that perimenopausal women who eat less fat still have high cancer rates. The Times evidently does not understand that modestly reducing fat and eating more chicken and pasta is not an anti-cancer program.

We are losing the war on cancer, and our government policies are actually worsening the problem. With all of the recent advances in science pointing to phytonutrient deficiency as the major cause of cancer, our efforts should focus on prevention; educating the public about proper diet and nutrition. Millions of lives can be saved. We also can eliminate the tragic consequences and family trauma of living with cancer---diagnoses, surgeries, radiation, chemotherapies, suffering, and premature death, which come from the cancer and very often from the treatment.

Avoiding Cancer
Your body is a self-repairing and self-healing machine. Human cells have all the features necessary to protect themselves from chemical damage to their DNA that eventually results in carcinogenic changes. A cancer cell is essentially a normal cell whose DNA has been damaged to the point that it can no longer control its replication. The process that is creating our modern epidemic of cancer is twofold. One aspect involves the exposure of our cells to damaging stresses such as chemical carcinogens, radon, acrylamides, and high levels of saturated and trans fats and animal protein. At the same time, we have a woefully insufficient dietary intake of plant-derived nutrients, which renders our cells incapable of functioning to their fullest potential for repair and maintenance.

Our cells have built-in, powerful mechanisms to remove or destroy toxic substances, inhibit DNA damage, repair broken DNA cross-links, and remove cells that are injured or abnormal before they become cancerous. In recent years, the term phytochemicals has been used to refer to the thousands of newly-discovered nutrients supplied by plants that---in addition to vitamins and minerals---are necessary for maximal immune system protection and for the promotion of cellular detoxification and repair.

Most of our knowledge about what constitutes the optimal cancer prevention diet comes from both human population (epidemiological) studies and animal studies. Populations that have a high intake of natural, unrefined plant foods such as fruits, vegetables, seeds, nuts, and beans always have a low incidence of cancer, proportional to the intake of these phytochemcal-rich plant foods.

Even though other factors such as chemicals, pollution, and smoking play a role in cancer etiology, the scientific literature still illustrates that a better diet offers dramatic protection even against nondietary cancer promoters. For example, the Fiji Islands (where smoking rates are high) still has a dramatically lower incidence of lung cancer than Hawaii (where smoking rates are lower). This protection against lung cancer even in heavily smoking Fiji Islanders was shown to be the result of the high intake of green vegetables in Fiji.4

Examining data from numerous epidemiological studies, the World Cancer Research Fund concluded that the evidence that fruits and vegetables may reduce the risk of oral, esophageal, lung, stomach, colon, pancreatic, bladder, and breast cancer was convincing. No single substance in a plant-based diet accounts for this relationship; rather, it is the synergistic effect of multiple phytochemical compounds (which number in the thousands).

The National Cancer Institute recommends eating 5 servings of fruits and vegetables each day. However, scientific studies suggest that more is better and that much, much more is much, much better at reducing cancer risk. It is a national disgrace that very few Americans follow this very minimal recommendation to eat 5 servings of fruits and vegetables daily.

Cruciferous Vegetables
While fruits and vegetables are excellent sources of nutrients, the consumption of vegetables is more helpful in reducing cancer because they contain much higher amounts of cancer-protective compounds-- especially green vegetables. Among these green vegetables, the cruciferous family has demonstrated the most dramatic protection against cancer. Cruciferous vegetables (broccoli, brussels sprouts, cauliflower, kale, bok choy, collards, arugala, watercress, and cabbage) contain a symphony of phytonutrients with potent anti-cancer effects. Isothiocyanates (ITCs), which are perhaps the best studied, have been shown to provide protection against environmental carcinogen exposure by inducing detoxification pathways, thereby neutralizing potential carcinogens.

These vegetables also contain indole-3- carbinol (I3C). Indole-3-carbinol has been shown to reduce the risk of breast cancer by decreasing estrogen activity. Important recent studies have shown that cruciferous vegetables and the compounds they contain can do the following:


  • halt the growth of breast cancer cells;5
  • dramatically reduce the risk of colon cancer;6
  • prevent the replication of prostate cancer cells and induce death of cancerous cells;7
  • inhibit the progression of lung cancer.8


What makes these studies even more fascinating is the discovery of the gene/diet interaction, which has shown that high intake of greens and cruciferous vegetables provides the food factors necessary to interact with--and prevent-- genetic defects from creating disease. This gene/diet interaction activates a battery of many genes, initiating DNA repair and other protection mechanisms.

These cellular repair and detoxification mechanisms are most powerfully induced by eating a mixture of both raw and cooked cruciferous plant foods. Some of the compounds are water soluble and heat stable, and absorption is increased when cooked, for example, in a soup. Other critical ITCs are heat sensitive and are better transmitted in the raw form.

Carotenoids & Polyphenols
Population studies show an association between high dietary intake of carotenoid-containing fruits and vegetables and reduced risk of prostate, breast, and head and neck cancers. A high dietary intake of fruits and vegetables provides a spectrum of carotenoids, including alphacarotene, gamma-carotene, betacryptoxanthin, zeaxanthin, lutein, and lycopene.

Vegetable juices (carrot, tomato, spinach, and other greens) represent a particularly potent form of carotenoids. Scientists have demonstrated that drinking carrot juice significantly reduces free radical damage to genes. Tomato juice and cooked tomatoes rich in lycopene and other potent antioxidants help reduce the oxidation of the "bad" LDL cholesterol and also have been shown to dramatically help protect against cancer. Carotenoid-rich extracts of carrots and tomatoes have been shown to substantially inhibit the early stages of liver cancer in animals.

Fruits also contain various key phytochemicals. For example, resveratrol, found in grapes, has been reported to exert a variety of anticancer effects. Studies have demonstrated that resveratrol causes growth inhibition of human colon and breast cancer cells. Ellagic acid, found in strawberries, grapes, blueberries, raspberries, and blackberries, is another polyphenol that has demonstrated anticarcinogenic potential in animal studies.

This article is from the Healthy Times newsletter, a complete archive of which is available to members of DrFuhrman.com.

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Dietary Fiber and Colon Cancer

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In a Dec. 14 Journal of the American Medical Association (JAMA) report, Yikyung Park, ScD, et al. addresses the relation between dietary fiber intake and risk of colorectal cancer.1 The study examines the commercially accepted hypothesis that dietary fiber reduces the risk of colorectal cancer. The conclusion of the research revealed mixed results, including some instances where fiber supplementation did not decrease the risk of cancer:

The association between dietary fiber intake and risk of colorectal cancer has been inconsistent among observational studies and several factors may explain the disparity: potential biases in each study, the failure to adjust for covariates in the multivariate models, and the range of dietary fiber intake. Inconsistent results also have been reported from randomized clinical trials of dietary fiber supplementation on the recurrence of colorectal adenomas (precursors of colorectal cancer); most trials have found no reduced risk of adenoma recurrence with dietary fiber supplementation compared with placebo.2-5

A statistically significant reduction in risk of colorectal cancer with higher dietary fiber intake has been observed in most case-control studies.6 However, case-control studies are prone to recall bias because dietary assessments are obtained after cancer diagnosis and also are prone to selection bias because control participants who participate are likely to be particularly health-conscious. In addition, publication bias may contribute to the accumulation of literature with significant findings. On the other hand, the Pooling Project is less susceptible to these biases because diet was assessed prior to diagnosis and the studies were not required to have published on the association between dietary fiber intake and risk of colorectal cancer.


In Dr. Fuhrman's book Eat to Live he gives a reason why this connection is inconsistent and provides his recommendation for fiber intake:
It is not the fiber extracted from the plant package that has miraculous health properties. It is the entire plant package considered as a whole, containing nature's anti-cancer nutrients as well as being rich in fiber.

High-fiber foods offer significant protection against both cancer (including colon cancer) and heart disease. I didn't say fiber; I said high-fiber foods. We can't just add a high-fiber candy bar or sprinkle a little Metamucil on our doughnut and french fries and expect to reap the benefits of eating high-fiber foods.

The reality is that healthy, nutritious foods are also very rich in fiber and that those foods associated with disease risk are generally fiber-deficient. Meat and dairy products do not contain any fiber, and foods made from refined grains (such as white bread, white rice, and pasta) have had their fiber removed. Clearly, we must substantially reduce our consumption of these fiber-deficient foods if we expect to lose weight and live a long, healthy life.


Furthermore, in his book Disease-Proof Your Child Dr. Fuhrman tells how the changing Japanese diet demonstrates a connection between higher consumption of animal products and the incidence of colon cancer:
The intake of Total Dietary Fiber (TDF) was evaluated from data from the National Nutrition Survey in Japan for forty-one years beginning in 1947. TDF intake decreased rapidly from 27.4 grams per day in 1947 to 15.8 grams in 1963. Fat intake increased rapidly from 18 grams in 1950 to 56.6 grams in 1987. Of significance in this carefully done study was that the increased occurrence of colon cancer had a twenty-three-to-twenty-four-year lag after the heightened consumption of animal products began. Apparently what the Japanese people did twenty-five years earlier had the strongest effect on inducing cancer, not what they ate ten years or even twenty years earlier.7 Those with the highest consumption of plant fiber in their childhood had the lowest incidence of colon cancer.

Recent studies have also found that eating fruit during childhood had powerful effects to protect against cancer in later life. A sixty-year study of 4,999 participants found that those who consumed more fruit in their childhood (the highest quartile) were 38 percent less likely to develop cancer as adults.8

Diets rich in meat and dairy are powerfully implicated as cancer promoters. Processed, pickled, smoked, or barbequed meats are even more strongly linked to cancer. Separate studies from Europe and the United States found the same results; those who eat meat daily have a three- to four-fold increase incidence of colon, esophageal, and stomach cancers, and the risks are more severe the younger in age people begin these practices.9

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NYTimes Tackles Cancer Prevention Through Exercise

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A few weeks ago, Gina Kolata of The New York Times wrote the first in a series about diet's role in preventing cancer. Dr. Fuhrman wrote a lengthy response (one of his main points: by ignoring the influence of diet during childhood, she missed the major nutrition/cancer link).

Today marks the second article in Ms. Kolata's cancer prevention series, and it focuses on exercise. The article is well worth a read. While I'm sure there are those who would argue some of her conclusions, she touches on a lot of the same issues that Dr. Fuhrman often talks about--like the early onset of menstruation and its effect on breast cancer rates (one doctor she quotes, for instance, says girls only begin menstruating when they have excess calories).

But what struck me most was the clear presentation of a rather sad notion: we Americans seem to not want to learn from the best medical research, if it means doing "boring" things like eating right and exercising.

The article quotes several studies and doctors making clear that there is a strong correlation between exercise and colon cancer. But doctors who prescribe exercise have little luck:

"I'm pretty confident it will work," Dr. Sandler said of the exercise prescription. But, he adds, most patients dismiss that advice.

"They kind of blow me off," he said.

Dr. John Min, an internist in private practice in Burlington, N. C., loves exercise - he runs in marathons - and he believes it can improve health and possibly protect people from colon and breast cancer. But he does not even mention it to his patients as a way to protect against those cancers.

"Unfortunately, trying to get patients, even those who are very interested, to start exercising is very difficult," he says.

He said he has tried, and patients have left his office seeming excited about turning their life around. But they soon return to their sedentary ways.

"This is unfortunately what I have realized," Dr. Min said. "The ability for someone to significantly change their lifestyle, which they've lived with for years, is extremely difficult unless it is personally important to them. I can't make it personally important to them in the time of an office visit."


Hmm... that's seriously too bad. I'm interested in any ideas people might have about smart tactics to change that reality. Who knows how much healthier we would all be if we did simple, low-tech things like ate right and exercised?

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