Disease Proof : Disease Proof : Health & Nutrition News & Commentary : Dr. Joel Fuhrman

Statins are a class of drugs used to treat elevated LDL cholesterol levels. Recently, researchers carried out a meta-analysis of 13 statin vs. placebo trials. Collectively, these researchers included over 90,000 subjects in their analysis, and came to the conclusion that taking statin drugs to lower cholesterol increases the likelihood of being diagnosed with diabetes by 9% over the following four years.¹

This is in fact the second meta-analysis performed in the past few months to come to this conclusion – an analysis published in October 2009 determined that statins increased diabetes risk by 13%. ²

Nine percent (or even 13%) may seem like a small risk, but let’s think about how many people take statin drugs. Today, cholesterol-lowering medications are the 2^nd most prescribed drug class in the U.S. (behind only pain relievers).³ Between 1988 and 2006 the use of statin drugs in U.S. adults over 45 increased 10-fold.⁴ 

Currently, over 30 million Americans take statin drugs, and this number may increase further. Statins may soon be recommended to older Americans who have normal LDL levels but elevated C-reactive protein.⁵ 

Each one of these millions of people will have a 9% increased risk of diabetes – when they could have used a high nutrient diet to lower their LDL and reduce their cardiovascular risk. A high nutrient diet rich in unrefined plant foods can reduce cholesterol to the same extent as statin drugs.⁶ Since reducing cholesterol with diet and exercise addresses the cause of the high cholesterol (the typical American diet), there will be no risk involved – in fact, it will also lead to weight loss, which will then reduce diabetes risk.

Statins are not benign substances – they are powerful drugs with side effects that include muscle pain and liver damage. Which would you choose to lower your LDL – statin drugs plus increased diabetes risk and potential liver and muscle damage, or dietary changes that reduce blood pressure, reverse and prevent diabetes and protect against dementia? My view is that drugs also have the psychological effects to inhibit the necessity of lifestyle and dietary changes that are the root cause of almost all our nation’s medical problems. Any way you look at it drugs kill millions of people and drug-centered health care is the problem, not the solution to our heath crisis and tremendous medical suffering.

References:

1. Sattar N et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet. 2010 Feb 16. [Epub ahead of print]

2. Rajpathak SN et al. Statin therapy and risk of developing type 2 diabetes: a meta-analysis. Diabetes Care. 2009 Oct;32(10):1924-9.

3. http://www.cdc.gov/nchs/FASTATS/drugs.htm

4. http://www.cdc.gov/nchs/pressroom/10newreleases/hus09.htm

5. Spatz ES et al.  From here to JUPITER: identifying new patients for statin therapy using data from the 1999-2004 National Health and Nutrition Examination Survey. Circ Cardiovasc Qual Outcomes. 2009 Jan;2(1):41-8. Epub 2009 Jan 13.

6. Jenkins DJ et al. Effect of a very-high-fiber vegetable, fruit, and nut diet on serum lipids and colonic function. Metabolism. 2001 Apr;50(4):494-503.

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Oh, those silly low-carb diets. Will they ever learn! Here’s more bad news for low-carb. A new study in the journal Proceedings of the National Academy of Sciences found low-carb, high-protein diets damage arties:

Diets based on eating lots of meat, fish and cheese, while restricting carbohydrates have grown in popularity in recent years.

But the Beth Israel Deaconess Medical Center in the US found such habits caused artery damage in tests on mice.

The researchers and independent experts both agreed a balanced diet was the best option…

…Lead researcher Anthony Rosenzweig said the findings were so concerning to him that he decided to come off the low-carb diet he was following.

He added: "Our research suggests that, at least in animals, these diets could be having adverse cardiovascular effects.

"It appears that a moderate and balanced diet, coupled with regular exercise, is probably best for most people."

And in 2007, a study found low-carb diets, like Atkins, cause long-term damage to blood vessels. Dr. Fuhrman is no fan of high-protein diets, all that saturated fat and insufficient plant nutrients increases risk of heart disease and cancer:

The Atkins diet (and other diets rich in animal products and low in fruits and unrefined carbohydrates) is likely to significantly increase a person's risk of colon cancer. Scientific studies show a clear and strong relationship between cancers of the digestive tract, bladder, and prostate with low fruit consumption. What good is a diet that lowers your weight but also dramatically increases your chances of developing cancer?

A meat-based, low-fiber diet, like the one Atkins advocates, includes little or no fruit, no starchy vegetables, and no whole grains. Following Atkin's recommendations could more than double your risk of certain cancers, especially meat-sensitive cancers, such as epithelial cancers of the respiratory tract.1 For example, a study conducted by the National Cancer Institute looked at lung cancer in nonsmoking women so that smoking would not be a major variable. Researchers found that the relative risk of lung cancer was six times greater in women in the highest fifth of saturated-fat consumption than those in the lowest fifth.

I asked Dr. Fuhrman to comment on this study. He chuckled at the news, saying, “This study definitely proves once and for all that mice should not be eating the Atkins diet. They should get Jenny Craig. Furthermore, vegetables make pigs fat, so maybe we shouldn't eat them either.”

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Not getting enough vitamin D can be harmful, just last week a report found lack of vitamin D heightens risk of metabolic syndrome and now researchers have found not getting enough vitamin D raises cholesterol.

[Researchers] obtained macrophage cells from diabetics and non-diabetics, with and without vitamin D deficiency. When the cells were exposed cells to cholesterol and low vitamin D levels, they found that low vitamin D levels in the culture dish resulted in fewer macrophages becoming foam cells.

On the other hand, when the human macrophages were placed in a vitamin D-rich environment, the uptake of cholesterol was suppressed, and they don't become foam cells, said Bernal-Mizrachi.

The researchers noted that it may be possible to delay or reverse the development of atherosclerosis in diabetics by helping them regain adequate vitamin D levels.

Recently, in a post of about children and their need for vitamin D, Dr. Fuhrman explains it get be difficult to get sufficient vitamin D from food, unless you are spending a lot time outdoors, and even then its tough.

A sufficient amount of vitamin D is difficult to obtain from dietary sources. It is possible to obtain vitamin D from direct sun exposure—without sunscreen (sunscreens block UV-B rays they in turn prevent the body from converting vitamin D). However, since the generous amount of sunshine necessary to assure sufficient vitamin D exposure is potentially harmful and because children often spend too much time indoors watching television, playing video games, or on the computer, it is advisable for all children to assure vitamin D levels with supplements, not sunshine.

To help you get your vitamin D, Dr. Fuhrman recommends his supplement Osteo-Sun, for both children and adults.

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I’m demented already, so I might not be the best person to talk about this, but new research in the journal Dementia and Geriatric Cognitive Disorders claims keeping cholesterol levels in check, i.e. low, reduces your likelihood of Alzheimer's disease.

Between 1994 and 2007, a review of their medical records showed that 469 had Alzheimer's disease and 127 had vascular dementia, the second most common form of dementia after Alzheimer's disease, which is caused by clogged blood vessels and other conditions affecting the blood supply to the brain.

Compared to people with "desirable" cholesterol levels below 200 milligrams per deciliter of blood (mg/dL) in midlife, the risk of Alzheimer's disease three decades later was 57 percent higher in people with high midlife cholesterol levels of 240 mg/dL and above.

"Borderline" high cholesterol (200 to 239 mg/dL) tended to increase the risk of Alzheimer's disease as well, but the results were not statistically significant.

Or, you can just avoid problem altogether. A plant-based diet staves of heart disease and lowers blood pressure and cholesterol. Now, I think eating vegetables is better than going nuts—right?

Via Reuters.

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I love berries. I eat a bunch of blueberries everyday. Good thing a new study in American Journal of Clinical Nutrition claims consuming a lot anthocyanins—a nutrient found in blueberries—may improve both HDL and LDL cholesterol, i.e. raise good cholesterol and lower bad.

Using a double-blind, randomized, placebo-controlled trial design, the Chinese researchers studied the effects of a twice daily dose of 160 mg anthocyanins on the lipid levels of the participants.

After 12 weeks of supplementation, HDL cholesterol levels increased by almost 14 per cent in the anthocyanin group, compared to a rise of only 2.8 per cent in the placebo group. Furthermore, LDL cholesterol levels decreased by 13.6 per cent in the anthocyanin group, compared to an increase of 0.6 per cent in the placebo group.

The removal of cholesterol from cells, the so-called cellular cholesterol efflux, was found to increase by 20 per cent in the anthocyanin group, compared to a 0.2 per cent in the placebo group.

Listen, fruits and vegetables are loaded with all sorts of nutrients. Anthocyanins are just the tip of the iceberg. Other foods like concord grapes and prunes are good sources of anthocyanins too.

Via Nutra Ingredients.

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I’m not like most physicians when it comes to treating hypertension. I’m not quick to prescribe medications; instead I advocate a non-drug centered approach to reverse heart disease and lower blood pressure. In my medical practice I have helped thousands of patients realize dramatic reduction in blood pressure, sometimes in as little as one week, simply by helping them adapt to my nutrient diet style and exercise program. In fact, I believe the conventional method of drug treatment is actually creating more heart attacks, strokes, and chronic disease than saving lives.

My July 2008 Healthy Times Newsletter, on treating high blood pressure, I outline the primary reasons that diet and lifestyle changes are so much safer and more effective than hypertension drug therapy, including:

• Nutritional excellence, weight loss, salt avoidance, and exercise are proven to be the safest and most effective at providing cardio-protective benefits - actually reversing blood vessel plaque and getting rid of high blood pressure.

• Medications have risks and side effects that can be life threatening.

• Excessive lowering of diastolic blood pressure in the elderly and those on medication to control significant coronary artery disease actually increases the risk of heart attack.1

This newsletter offers detailed information about the risks and overuse of blood pressure medication and recent research findings corroborate my approach for lowering blood pressure.

According to a Cochrane Review treating patients with medications to reach lower blood pressure targets below the standard 140/90 did not show any reduction in morbidity and mortality. The researchers conducted a meta-analysis of over 22,000 adults with hypertension taking anti-hypertension medication which indicated a higher risk for total mortality and a relatively significant increased risk of major cardiovascular events with more aggressive use of medications.

High blood pressure (BP) is defined as having a systolic (the upper number) blood pressure above 140 and a diastolic (the lower number) blood pressure above 90 mmHg. High blood pressure is a risk factor for increased risk of heart attack and stroke. As a result this range has become the standard blood pressure target for physicians and patients. A recent trend toward lower targets has been recommended by hypertension experts who set treatment guidelines. This trend is based on the assumption that the use of drugs to bring the BP lower than 140/90 mmHg range will reduce the risk of heart attack and stroke. However, this approach was proven false even in high risk patients.

The review was performed to find and assess all trials designed to examine whether lower blood pressure targets are better than standard blood pressure targets. When the data was analyzed, it revealed that using more drugs in the lower target groups did achieve modestly lower blood pressures. However, this approach did not prolong survival or reduce stroke, heart attack, heart failure or kidney failure.2

Blood pressure medications are especially a concern when medication lowers the diastolic number too low. When the diastolic blood pressure is lowered excessively (as they lower systolic pressure), it increases the potential for cardiac arrhythmias that can lead to death.3 The excessive use of blood pressure medications that lower diastolic blood pressure too low also have been shown to increase the occurrence of atrial fibrillation, another serious rhythm disturbance of the heart.4

I have been educating my patients and readers about this for many years and now this meta-analysis provides even more scientific evidence that supports my recommendations--to avoid heart attack and stroke, the goal is not just to achieve a systolic blood pressure below 130; you must achieve it without medication!

Learn more about why using drugs to treat hypertension is dangerous and ineffective in my July 2008 Healthy Times Newsletter.

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In college, the only citrus I got was the lime in my beer bottle, but now I know better. Citrus fruits are loaded with health-promoting nutrients, like vitamin C.

Kiwi fruit, watermelon, strawberries, mangos and raspberries are all packed with vitamin C. And in May, vitamin C was found to stave off age-related vision loss.

Now, new findings in the journal Diabetes claims another fruit nutrient, naringenin—a flavonoid in citrus fruits—halts the development of metabolic syndrome, which leads to diabetes, heart disease and obesity.

For the study, scientists fed mice a high-fat diet—to simulate a western diet—in order to induce symptoms of metabolic syndrome and discovered mice fed a fatty diet plus naringenin had “corrected” levels of triglycerides and cholesterol.

Naringenin also protected against insulin resistance. Experts say naringenin reprogrammed the liver to burn up excess fat, instead of storing it. However, more research is needed to determined naringenin’s exact effect on heart disease.

In related news, pomegranates were found to reduce inflammation associated with cardiovascular disease.

Via EurekAlert!

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A lot of people think a healthy diet means grilled chicken and pasta. Nope. Try again. In his book Cholesterol Protection for Life, Dr. Fuhrman explains chicken—and even lean meats—don’t do much to lower cholesterol. In this discussion from the member center, Dr. Fuhrman explains why foods like chicken and shrimp aren’t wise choices for heart health:

Question: I remember reading a while back that chicken and shrimp are low in fat but high in cholesterol. Is that true? My friend has a heart condition and his nutritionist told him shrimp and chicken were good to eat depending on how it was cooked. I would like to convince him otherwise. First, I want to make sure I have my facts straight.

Dr. Fuhrman: Animal products, including high protein white meat chicken raise cholesterol, not just because of its saturated fat and cholesterol content, but because animal protein also raises cholesterol. Secondly, it is not just about cholesterol. You must reduce low-phytochemical and low-antioxidant foods like animal products and leave room for the high-nutrient plant foods.

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You hear a lot of LDL cholesterol, i.e. bad cholesterol, but HDL cholesterol—the good stuff—is just as important to heart health, especially when you’re losing weight. In this quick discussion from Dr. Fuhrman’s member center, he talks about LDL, HDL, weight-loss and fasting:

Question: My HDL went from 26 to 21. My cardiologist told me to eat more avocados to improve it. I did and my weight responded immediately. I gained weight. I think this was a bad idea. Am I right?

Also, I heard you say that the best treatment for heart disease is a combination of nutrition and fasting, but I read in your book it's not wise to fast if you're overweight. I went from 245 to 210 on Eat to Live in a few months, but I'm still overweight.

So I am confused. On the one hand, you say don't do fast when you're overweight, but on the other hand, you recommend fasting instead of do surgery.

Dr. Fuhrman: Listening to the nutritional advice of typical doctors is like asking your mailman for advice on your taxes. They typically have little knowledge or experience. Focusing on HDL and not your weight is a mistake.

A low HDL reading is of no practical consequence, just get rid of your plaque and keep LDL low. A high HDL can benefit a person with a higher LDL, but a low HDL does not hurt a person with a favorable, low LDL.

Weight loss is much more important than your lipid numbers because the plaque can be reduced most effectively once you have reached a lower body fat percentage, i.e. below 10%.

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New research in the Archives of Internal Medicine claim plant-based diets promote weight-loss and reduce risk of heart disease. For the study, participants—overweight men and women with high LDL—were fed a diet rich in vegetables, nuts and fruits or a typical low-fat diet. Findings revealed both groups lost weight, but people on the vegetable-based diet had better cholesterol levels and lower blood pressure. Here are Dr. Fuhrman’s thoughts on the study:

It’s a pretty good effort. They are getting closer to the ideal diet—a nutritarian diet—by studying a vegetarian diet with reduction of flour and other high glycemic carbohydrates.

Of course, the results are pretty good, but it is evident these researchers lack the knowledge and clinical experience designing a diet-style for nutritional excellence.

We have a pilot study coming out shortly with results that dwarf this, but clearly we at the Eat Right America Foundation are in need of funding to begin our larger study on diabetics.

Via Newswise.

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