Drugs used to treat preventable diseases carry serious risks (Part 1 - statins)

Never forget, you don’t get something for nothing when it comes to medications. All medications have side effects, most of them potentially serious.Typically a drug has to be on the market for many years to discern all the long-term risks. Recently, news has come out exposing serious adverse effects of two types of drugs that are used to treat high cholesterol and high blood pressure – statins and angiotensin receptor blockers.  The pharmaceutical industry performing their own “research” has a long and consistent record of covering up discovered dangers of their products and embellishing the advantages. Of course, physicians also give the impression that drugs are necessary, when in fact they are not. 

Pill bottle

 

1. Statins – cholesterol-lowering drugs

Researchers examined medical records of over 2 million statin users in England and Wales in order to quantify side effects during the first 5 years of statin use.

The conditions that were found to be associated with statin use were:

  • Moderate to serious liver dysfunction
  • Acute renal failure
  • Moderate to serious myopathy (impaired muscle function)
  • Cataracts1

Statins have also been linked to increased diabetes risk in another recent study.

Statins, which block a key enzyme in the body’s production of cholesterol, are the most widely prescribed class of drugs in the U.S. Statin use is growing, and will soon be expanding even to those who do not have elevated LDL levels, based on the recent (drug-company funded) JUPITER study.2 More widespread statin use will continue to give Americans a false sense of security, that they are protected from cardiovascular disease when they are only treating a single symptom. Only excellent nutrition, not drugs, can provide complete protection against heart disease. With widespread use of statins, the nutritional causes of heart disease are not addressed, and a significant number of liver dysfunction, renal failure, myopathy, and cataract cases will be produced. The authors of the statin adverse effect study stressed that physicians should weigh the possible risks and benefits before placing someone on a statin. But since it is rare that a person (on a nutritarian diet) would actually require a statin, realistically the benefits do not weigh heavily. These adverse effects are simply unacceptable when the alternative to these drugs is a nutrient-dense diet and exercise, treatments with only positive side effects.

 

References:

1. Hippisley-Cox J, Coupland C. Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database. BMJ 2010 May 20;340:c2197.

2. Spatz ES et al. From here to JUPITER: identifying new patients for statin therapy using data from the 1999-2004 National Health and Nutrition Examination Survey. Circ Cardiovasc Qual Outcomes. 2009 Jan;2(1):41-8.

Interview with a nutritarian: Mike

Recently Mike posted a thread titled, “Down 10 pant sizes!” on the member center of DrFuhrman.com.  I asked him if he’d be willing to be interviewed on Disease Proof to inspire others to get their health back also, and he graciously obliged to share his story.  Not only did he drop pants sizes, but also his bottles of medications.  Welcome to Disease Proof, Mike!   

before after pics of male nutritarian

What was your life like before discovering Dr. Fuhrman’s nutritarian eating-style?

Due to unhealthy eating habits, including eating out too much, I had been getting heavier and slowing down with each passing birthday. At age forty I weighed 165 lbs; at fifty I weighed 195 lbs; and at sixty I weighed 215 lbs.  I’d always been active at playing golf, surf fishing and cycling.  However, the extra weight made a walk around the golf course an adventure, surf fish very tiring, and small hills on bike rides seemed like pedaling the Alps.  I was also getting tired at work and needed stimulants to make it through the second part of each day. I was a fixture at the local chocolate shop as I needed a shot of chocolate to get me through the afternoons.
 
I was scared because I started having chest pains while climbing stairs, hiking hills on the golf course, and in stressful situations. One day I encountered difficulty swallowing, followed by chest pains which landed me in the hospital. I ducked a heart attack, but tests revealed that my left descending lower artery was 50% blocked so they started me on aspirin, blood pressure meds and statins.


How did you find out about ETL?

I’d given up smoking in the mid 80’s and tried Pritkin, McDougall, and a few others to get healthy, but they required a lot of food preparation so I eventually quit following them.  When I got home from the hospital, I wanted to see if there was anything “new” on the market for healthy eating so I scoured the book section of the local health food store and discovered The China Study and Eat to LiveEat to Live was just what I was looking for: simple to shop for and prepare, with very little clean up.  This was perfect for me as I worked and wanted to be able to do most of the shopping, prep and cleaning myself. 

I visited Dr. Fuhrman for the first time in January 2009.  After I was weighed and measured (including my waist size and level of nutrients in my body), he clearly explained to me that I needed to follow the “straight and narrow” and lose a lot of weight pronto, or else suffer the consequences.  He told me that the extra fat on my mid section was probably as much responsible for my artery blockage as my cholesterol, because that fat produces plaque; an important reason not to be overweight!  I decided to listen to Dr. Fuhrman as he made a lot more sense to me than the cardiologist who was only interested in my cholesterol and blood pressure. 

 

How do you feel now?

ETL has given me 10 to 15 years of my life back!  I’m now off of all meds (statins and blood pressure lowering meds), and I feel better, look better, and think better than ever before; plus, I have the additional confidence that I’ll live a long and healthy life devoid of needing to see a cardiologist again!  I also don’t have to worry about developing diabetes (it runs in my family) or having a stroke, and eating lots of cruciferous vegetables, fruits and beans greatly reduces my risk of getting cancer. From a mental perspective this is huge as I’m a big believer that actively doing something is akin to moving forward under fire, and increases confidence and outlook on life. 

[At age 63, Mike recently finished a 102 mile bike ride in 6:10; and over Memorial Day weekend he completed a sixty mile ride with an “A” team of cyclists, and was able to hang with the group for the entire time.  He finds this to be unbelievable, because two years ago he was afraid to ride to with “C” cyclists, because he didn’t think that he could keep up with them.  Now he’s approached by some of the top riders and asked, “What’s the name of that book you told me about?”!]

 

 

before

now

Weight

216 lbs

158 lbs

Waist measurement

  43”

  33”

Blood pressure

145/90 (with meds)

115/70 (no meds)

Cholesterol

165 (105/35 ratio)

125 (60/45 ratio)

 

Do you have any success tip(s) to share with others?

Nutritarian eating is a simple and healthful way to eat that combats all major and chronic diseases killing modern man . . . so go for it!  You won’t be sorry!
 
Also, when I first read Dr. Fuhrman’s claims, and even after I’d met him, I wasn’t so sure if I was being taken as it seemed too simple: Greens to the rescue? No meds? No fancy formulas?  All these things sounded too good to be true, but I found everything to be true! 

Don’t wait for fear of a heart attack to be motivated to change!

 

Congratulations Mike ~ we applaud you for getting your health back!

New findings on nuts and cholesterol

Nuts have been consistently associated with reduced risk of coronary heart disease in epidemiological studies.1 Evidence of nuts’ cardioprotective effects were originally recognized in the early 1990s2, and since then, several human trials have documented improvements in lipid levels in response to including nuts in the diet.3 Beneficial cardiovascular effects beyond cholesterol lowering have also been identified, particularly for walnuts and almonds.

Walnuts

A review published recently in Archives of Internal Medicine pooled the data from 25 different clinical studies that ran for a minimum of three weeks, comparing a nut eating group to a control group. Most of the studies were done on walnuts or almonds, but studies on macadamias, pistachios, hazelnuts, pecans, and peanuts were also included in the analysis.4,5

This review confirmed that nut consumption has beneficial effects on lipid levels,  and it also reached two interesting new conclusions: 

1. Dose dependent effect

First, the different studies were on different quantities of nuts, and the review concluded that the cholesterol-lowering effects of nuts are dose-dependent – this means that more nuts consumed translated into greater decreases in LDL and total cholesterol:

Quantity of nuts consumed

Decrease in total cholesterol

Decrease in LDL

1 oz.

2.8%

4.2%

1.5 oz.

3.2%

4.9%

2.4 oz.

5.1%

7.4%

For healthy weight individuals, these results suggest that 2.4 ounces may be better than 1 ounce for cardiovascular health.4,5

2. Effects were greater in individuals with lower BMI

The researchers found that body mass index (BMI) modified the association between nut consumption and cholesterol lowering. The effects of nuts were greater in individuals with lower BMI, meaning that those who were overweight or obese saw less cholesterol-lowering benefit than healthy weight individuals.4,5

Nuts and seeds are critical components of a disease-preventing diet, and I recommend eating them daily. However, I also recommend a limit of 1 ounce of nuts and seeds per day for individuals who are overweight. The results of this study support my recommendations. For those that are overweight, nuts are beneficial, but weight loss is even more important. The primary means of decreasing cardiovascular risk in overweight individuals should be eating lots of high micronutrient, low calorie foods. For people significantly overweight, nuts should still be included, but their caloric density suggests a limit such as 1 ounce per day for women and 1.5 ounces a day for men.

Wondering how many nuts are in a 1 ounce serving? The International Tree Nut Council’s website provides a guide to 1 ounce serving sizes of several different nuts.


References:

1. Sabaté J, Ang Y. Nuts and health outcomes: new epidemiologic evidence. Am J Clin Nutr. 2009 May;89(5):1643S-1648S.

2. Fraser GE, Sabate J, BeesonWL, Strahan TM. A Possible Protective Effect of Nut Consumption on Risk of Coronary Heart Disease: The Adventist Health Study. Arch Intern Med. 1992;152(7):1416-1424.

3. Griel AE, Kris-Etherton PM. Tree nuts and the lipid profile: a review of clinical studies. Br J Nutr. 2006 Nov;96 Suppl 2:S68-78.

4. Sabaté J, Oda K, Ros E. Nut consumption and blood lipid levels: a pooled analysis of 25 intervention trials. Arch Intern Med. 2010 May 10;170(9):821-7.

Eurekalert! Eating nuts associated with improvements in cholesterol levels: http://www.eurekalert.org/pub_releases/2010-05/jaaj-ena050610.php

Cholesterol-lowering drugs may raise diabetes risk

Statins are a class of drugs used to treat elevated LDL cholesterol levels. Recently, researchers carried out a meta-analysis of 13 statin vs. placebo trials. Collectively, these researchers included over 90,000 subjects in their analysis, and came to the conclusion that taking statin drugs to lower cholesterol increases the likelihood of being diagnosed with diabetes by 9% over the following four years.1

This is in fact the second meta-analysis performed in the past few months to come to this conclusion – an analysis published in October 2009 determined that statins increased diabetes risk by 13%. 2

Nine percent (or even 13%) may seem like a small risk, but let’s think about how many people take statin drugs. Today, cholesterol-lowering medications are the 2nd most prescribed drug class in the U.S. (behind only pain relievers).3 Between 1988 and 2006 the use of statin drugs in U.S. adults over 45 increased 10-fold.4 

Currently, over 30 million Americans take statin drugs, and this number may increase further. Statins may soon be recommended to older Americans who have normal LDL levels but elevated C-reactive protein.5 

Each one of these millions of people will have a 9% increased risk of diabetes – when they could have used a high nutrient diet to lower their LDL and reduce their cardiovascular risk. A high nutrient diet rich in unrefined plant foods can reduce cholesterol to the same extent as statin drugs.6 Since reducing cholesterol with diet and exercise addresses the cause of the high cholesterol (the typical American diet), there will be no risk involved – in fact, it will also lead to weight loss, which will then reduce diabetes risk.

Statins are not benign substances – they are powerful drugs with side effects that include muscle pain and liver damage. Which would you choose to lower your LDL – statin drugs plus increased diabetes risk and potential liver and muscle damage, or dietary changes that reduce blood pressure, reverse and prevent diabetes and protect against dementia? My view is that drugs also have the psychological effects to inhibit the necessity of lifestyle and dietary changes that are the root cause of almost all our nation’s medical problems. Any way you look at it drugs kill millions of people and drug-centered health care is the problem, not the solution to our heath crisis and tremendous medical suffering.

 

References:

1. Sattar N et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet. 2010 Feb 16. [Epub ahead of print]

2. Rajpathak SN et al. Statin therapy and risk of developing type 2 diabetes: a meta-analysis. Diabetes Care. 2009 Oct;32(10):1924-9.

3. http://www.cdc.gov/nchs/FASTATS/drugs.htm

4. http://www.cdc.gov/nchs/pressroom/10newreleases/hus09.htm

5. Spatz ES et al.  From here to JUPITER: identifying new patients for statin therapy using data from the 1999-2004 National Health and Nutrition Examination Survey. Circ Cardiovasc Qual Outcomes. 2009 Jan;2(1):41-8. Epub 2009 Jan 13.

6. Jenkins DJ et al. Effect of a very-high-fiber vegetable, fruit, and nut diet on serum lipids and colonic function. Metabolism. 2001 Apr;50(4):494-503.

 

Ha Ha Ha! Low-Carb, High-Protein Diets Damage Arteries.

Oh, those silly low-carb diets. Will they ever learn! Here’s more bad news for low-carb. A new study in the journal Proceedings of the National Academy of Sciences found low-carb, high-protein diets damage arties:

Diets based on eating lots of meat, fish and cheese, while restricting carbohydrates have grown in popularity in recent years.

But the Beth Israel Deaconess Medical Center in the US found such habits caused artery damage in tests on mice.

The researchers and independent experts both agreed a balanced diet was the best option…

…Lead researcher Anthony Rosenzweig said the findings were so concerning to him that he decided to come off the low-carb diet he was following.

He added: "Our research suggests that, at least in animals, these diets could be having adverse cardiovascular effects.

"It appears that a moderate and balanced diet, coupled with regular exercise, is probably best for most people."

And in 2007, a study found low-carb diets, like Atkins, cause long-term damage to blood vessels. Dr. Fuhrman is no fan of high-protein diets, all that saturated fat and insufficient plant nutrients increases risk of heart disease and cancer:

The Atkins diet (and other diets rich in animal products and low in fruits and unrefined carbohydrates) is likely to significantly increase a person's risk of colon cancer. Scientific studies show a clear and strong relationship between cancers of the digestive tract, bladder, and prostate with low fruit consumption. What good is a diet that lowers your weight but also dramatically increases your chances of developing cancer?

A meat-based, low-fiber diet, like the one Atkins advocates, includes little or no fruit, no starchy vegetables, and no whole grains. Following Atkin's recommendations could more than double your risk of certain cancers, especially meat-sensitive cancers, such as epithelial cancers of the respiratory tract.1 For example, a study conducted by the National Cancer Institute looked at lung cancer in nonsmoking women so that smoking would not be a major variable. Researchers found that the relative risk of lung cancer was six times greater in women in the highest fifth of saturated-fat consumption than those in the lowest fifth.

I asked Dr. Fuhrman to comment on this study. He chuckled at the news, saying, “This study definitely proves once and for all that mice should not be eating the Atkins diet. They should get Jenny Craig. Furthermore, vegetables make pigs fat, so maybe we shouldn't eat them either.”

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Sunshine Vitamin - Vitamin D Helps Diabetics' Hearts

Not getting enough vitamin D can be harmful, just last week a report found lack of vitamin D heightens risk of metabolic syndrome and now researchers have found not getting enough vitamin D raises cholesterol.

[Researchers] obtained macrophage cells from diabetics and non-diabetics, with and without vitamin D deficiency. When the cells were exposed cells to cholesterol and low vitamin D levels, they found that low vitamin D levels in the culture dish resulted in fewer macrophages becoming foam cells.

On the other hand, when the human macrophages were placed in a vitamin D-rich environment, the uptake of cholesterol was suppressed, and they don't become foam cells, said Bernal-Mizrachi.

The researchers noted that it may be possible to delay or reverse the development of atherosclerosis in diabetics by helping them regain adequate vitamin D levels.

Recently, in a post of about children and their need for vitamin D, Dr. Fuhrman explains it get be difficult to get sufficient vitamin D from food, unless you are spending a lot time outdoors, and even then its tough.

A sufficient amount of vitamin D is difficult to obtain from dietary sources. It is possible to obtain vitamin D from direct sun exposure—without sunscreen (sunscreens block UV-B rays they in turn prevent the body from converting vitamin D). However, since the generous amount of sunshine necessary to assure sufficient vitamin D exposure is potentially harmful and because children often spend too much time indoors watching television, playing video games, or on the computer, it is advisable for all children to assure vitamin D levels with supplements, not sunshine.

To help you get your vitamin D, Dr. Fuhrman recommends his supplement Osteo-Sun, for both children and adults.

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Lower Cholesterol Cuts Risk of Dementia

I’m demented already, so I might not be the best person to talk about this, but new research in the journal Dementia and Geriatric Cognitive Disorders claims keeping cholesterol levels in check, i.e. low, reduces your likelihood of Alzheimer's disease.

Between 1994 and 2007, a review of their medical records showed that 469 had Alzheimer's disease and 127 had vascular dementia, the second most common form of dementia after Alzheimer's disease, which is caused by clogged blood vessels and other conditions affecting the blood supply to the brain.

Compared to people with "desirable" cholesterol levels below 200 milligrams per deciliter of blood (mg/dL) in midlife, the risk of Alzheimer's disease three decades later was 57 percent higher in people with high midlife cholesterol levels of 240 mg/dL and above.

"Borderline" high cholesterol (200 to 239 mg/dL) tended to increase the risk of Alzheimer's disease as well, but the results were not statistically significant.

Or, you can just avoid problem altogether. A plant-based diet staves of heart disease and lowers blood pressure and cholesterol. Now, I think eating vegetables is better than going nuts—right?

Via Reuters.

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Berry Nutrient Helps Improve Cholesterol

I love berries. I eat a bunch of blueberries everyday. Good thing a new study in American Journal of Clinical Nutrition claims consuming a lot anthocyanins—a nutrient found in blueberries—may improve both HDL and LDL cholesterol, i.e. raise good cholesterol and lower bad.

Using a double-blind, randomized, placebo-controlled trial design, the Chinese researchers studied the effects of a twice daily dose of 160 mg anthocyanins on the lipid levels of the participants.

After 12 weeks of supplementation, HDL cholesterol levels increased by almost 14 per cent in the anthocyanin group, compared to a rise of only 2.8 per cent in the placebo group. Furthermore, LDL cholesterol levels decreased by 13.6 per cent in the anthocyanin group, compared to an increase of 0.6 per cent in the placebo group.

The removal of cholesterol from cells, the so-called cellular cholesterol efflux, was found to increase by 20 per cent in the anthocyanin group, compared to a 0.2 per cent in the placebo group.

Listen, fruits and vegetables are loaded with all sorts of nutrients. Anthocyanins are just the tip of the iceberg. Other foods like concord grapes and prunes are good sources of anthocyanins too.

Via Nutra Ingredients.

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Lowering Blood Pressure Can Be Harmful...

I’m not like most physicians when it comes to treating hypertension. I’m not quick to prescribe medications; instead I advocate a non-drug centered approach to reverse heart disease and lower blood pressure. In my medical practice I have helped thousands of patients realize dramatic reduction in blood pressure, sometimes in as little as one week, simply by helping them adapt to my nutrient diet style and exercise program. In fact, I believe the conventional method of drug treatment is actually creating more heart attacks, strokes, and chronic disease than saving lives.

My July 2008 Healthy Times Newsletter, on treating high blood pressure, I outline the primary reasons that diet and lifestyle changes are so much safer and more effective than hypertension drug therapy, including:

  • Nutritional excellence, weight loss, salt avoidance, and exercise are proven to be the safest and most effective at providing cardio-protective benefits - actually reversing blood vessel plaque and getting rid of high blood pressure.
  • Medications have risks and side effects that can be life threatening.
  • Excessive lowering of diastolic blood pressure in the elderly and those on medication to control significant coronary artery disease actually increases the risk of heart attack.1

This newsletter offers detailed information about the risks and overuse of blood pressure medication and recent research findings corroborate my approach for lowering blood pressure.

According to a Cochrane Review treating patients with medications to reach lower blood pressure targets below the standard 140/90 did not show any reduction in morbidity and mortality. The researchers conducted a meta-analysis of over 22,000 adults with hypertension taking anti-hypertension medication which indicated a higher risk for total mortality and a relatively significant increased risk of major cardiovascular events with more aggressive use of medications.

High blood pressure (BP) is defined as having a systolic (the upper number) blood pressure above 140 and a diastolic (the lower number) blood pressure above 90 mmHg. High blood pressure is a risk factor for increased risk of heart attack and stroke. As a result this range has become the standard blood pressure target for physicians and patients. A recent trend toward lower targets has been recommended by hypertension experts who set treatment guidelines. This trend is based on the assumption that the use of drugs to bring the BP lower than 140/90 mmHg range will reduce the risk of heart attack and stroke. However, this approach was proven false even in high risk patients.

The review was performed to find and assess all trials designed to examine whether lower blood pressure targets are better than standard blood pressure targets. When the data was analyzed, it revealed that using more drugs in the lower target groups did achieve modestly lower blood pressures. However, this approach did not prolong survival or reduce stroke, heart attack, heart failure or kidney failure.2

Blood pressure medications are especially a concern when medication lowers the diastolic number too low. When the diastolic blood pressure is lowered excessively (as they lower systolic pressure), it increases the potential for cardiac arrhythmias that can lead to death.3 The excessive use of blood pressure medications that lower diastolic blood pressure too low also have been shown to increase the occurrence of atrial fibrillation, another serious rhythm disturbance of the heart.4

I have been educating my patients and readers about this for many years and now this meta-analysis provides even more scientific evidence that supports my recommendations--to avoid heart attack and stroke, the goal is not just to achieve a systolic blood pressure below 130; you must achieve it without medication!

Learn more about why using drugs to treat hypertension is dangerous and ineffective in my July 2008 Healthy Times Newsletter.

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Citrus Nutrient May Help Stop Obesity

In college, the only citrus I got was the lime in my beer bottle, but now I know better. Citrus fruits are loaded with health-promoting nutrients, like vitamin C.

Kiwi fruit, watermelon, strawberries, mangos and raspberries are all packed with vitamin C. And in May, vitamin C was found to stave off age-related vision loss.

Now, new findings in the journal Diabetes claims another fruit nutrient, naringenin—a flavonoid in citrus fruits—halts the development of metabolic syndrome, which leads to diabetes, heart disease and obesity.

For the study, scientists fed mice a high-fat diet—to simulate a western diet—in order to induce symptoms of metabolic syndrome and discovered mice fed a fatty diet plus naringenin had “corrected” levels of triglycerides and cholesterol.

Naringenin also protected against insulin resistance. Experts say naringenin reprogrammed the liver to burn up excess fat, instead of storing it. However, more research is needed to determined naringenin’s exact effect on heart disease.

In related news, pomegranates were found to reduce inflammation associated with cardiovascular disease.

Via EurekAlert!

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