Disease Proof

Vytorin Bad, Statins Good?

Vytorin is a bust, so, doctors are urging people “to turn back to statins.” Yeah, great idea! More from the Associated Press:
Millions of Americans already take the drug or one of its components, Zetia. But doctors were stunned to learn Vytorin failed to improve heart disease, even though it worked as intended to reduce three key risk factors.


"People need to turn back to statins," said Yale University cardiologist Dr. Harlan Krumholz, referring to Lipitor, Crestor and other widely used brands. "We know that statins are good drugs. We know that they reduce risks…"

…The study tested whether Vytorin was better than Zocor alone at limiting plaque buildup in the arteries of 720 people with super high cholesterol because of a gene disorder.

The results show the drug had "no result. In no subgroup, in no segment, was there any added benefit" for reducing plaque, said Dr. John Kastelein, the Dutch scientist who led the study.
Why are we so caught up with statins? It’s not like statins are some miracle. They’ve got loads of problems. Dr. Fuhrman explains:
The known side effects for various statins (the most popular and effective medications to lower cholesterol) include hepatitis, jaundice, other liver problems, gastrointestinal upsets, muscle problems and a variety of blood complications such as reduced platelet levels and anemia.
Alright damn it! Let’s talk side effects. Here are the know side effects of eating plenty of fruits and vegetables. More from Dr. Fuhrman:
The cholesterol-lowering effects of vegetables and beans (high-protein foods) are without question. However, they contain an assortment of additional heart disease-fighting nutrients independent of their ability to lower cholesterol.1 They fight cancer, too. Cancer incidence worldwide has an inverse relation with fruit and vegetable intake.2 If you increase your intake 80%, the risk of getting cancer drops 80%.
Now here’s a novel idea. Put down the cheeseburger, toss the statins out the window, and go for a jog—sheesh!

1. Forman D; Bulwer BE. “Cardiovascular disease: optimal approaches to risk factor modification of diet and lifestyle.” Curr Treat Options Cardiovasc Med 2006;8(1):47-57.

Bazzano LA; Serdula MK; Liu S. “Dietary intake of fruits and vegetables and risk of cardiovascular disease.” Curr Atheroscler Rep 2003;5(6):492-9.

2. Mai V; Kant AK; Flood A; et al. “Diet quality and subsequent cancer incidence and mortality in a prospective cohort of women.” Int J Epidemiol 2005;34(1):54-60.

Martinez ME. “Primary prevention of colorectal cancer: lifestyle, nutrition, exercise.” Recent Results Cancer Res 2005;166:177-211.

Giovannucci E. “Modifiable risk factors for colon cancer.” Gastroenterol Clin North Am 2002;31(4):925-43.
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Comments (3) Read through and enter the discussion with the form at the end
Llouise - April 1, 2008 10:29 AM

Yes, go for a jog! :^)
I saw a program on the aging the other night and what Dr. Fuhrman has been saying was reinforced: The aging (even those into their 90's) can literally reverse aging through exercise. Now imagine if they actually ate according to H=N/C also.
I'm feeling quite young today :^D

Gerry Pugliese - April 1, 2008 11:56 AM

Hey Llouise-

Agreed. I'm going to rent a sky-writing.

Peace.
-Gerry

Sara - April 1, 2008 9:26 PM

Go for a jog and then have some veggies for dinner.

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