Leafy green vegetables are super foods! There power is especially prevalent in the fight against cancer. Here’s some research from Dr. Fuhrman:
Halt the growth of breast cancer cells.
- Drug Discovery Today: “Sulforaphane is a chemical found in cruciferous vegetables such as broccoli, sprouts and kale. This compound is a potent inducer of protective enzymes that provide defense against cancer-causing chemicals. Researchers have discovered that sulforaphane can halt human breast cancer cells in their tracks and have identified a new mechanism of action for the compound.”
- Toxicology and Applied Pharmacology: “Taken together, our data indicate that isothiocyanates derived form broccoli and Rorripa inhibit metalloproteinase 9 activities and also suppress the invasive potential of human MDA-MB-231 breast cancer cells in vitro. The inhibitory effects observed in the current study may contribute to the suppression of carcinogenesis by diets high in cruciferous vegetables.”
Dramatically reduce the risk of colon cancer.
- Carcinogenesis: “Our results are compatible with the hypothesis that ITCs from cruciferous vegetables modify risk of colorectal cancer in individuals with low GST activity. Further, this gene-diet interaction may be important in studies evaluating the effect of risk-enhancing compounds in the colorectum.”
Prevent the replication of prostate cancer cells and induce death of cancerous cells.
- Journal of Agriculture and Food Chemistry: “A variety of studies have suggested a cancer protective role of cruciferous vegetables. In the present study, we investigated the effect of indole-3-carbinol (I3C), a major indole metabolite in cruciferous vegetables, on cell proliferation and in vitro markers of angiogenesis in phorbol myristate acetate (PMA)-stimulated endothelial EA hy926 cells. The results showed that I3C inhibited the growth of EA hy926 cells in a concentration-dependent manner.”
- Carcinogenesis: “Cruciferous vegetables are a rich source of ITCs that are highly effective in affording protection against cancers in experimental animals induced by a variety of chemical carcinogens (2–8). In the present study, we tested the hypothesis that ITCs may inhibit proliferation of human prostate cancer cells. We found that AITC significantly inhibited proliferation of PC-3 and LNCaP human prostate cancer cells in a concentration-dependent manner.”
Inhibit the progression of lung cancer.
Speaking of research, a new study has determined that isothiocyanates—a phytonutrient found in broccoli and other cruciferous vegetables fights cancer. Reuters reports:
- Cancer Research: “The results show that phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates given in the diet after lung adenomas have already developed could inhibit the progression to adenocarcinomas. The inhibitory effects of these compounds are likely to be associated with a combination of reduced cell proliferation and induced apoptosis. These findings are important for future research of lung cancer chemoprevention and therapy in smokers and ex-smokers with early lesions.”
The researchers also took tissue samples over the course of the study and found that men who ate broccoli showed hundreds of changes in genes known to play a role in fighting cancer.Makes me feel extra good about the steamed broccoli I ate last night! Here’s a quick quote from Dr. Fuhrman on isothiocyanates. Have a look:
The benefit would likely be the same in other cruciferous vegetables that contain a compound called isothiocyanate, including brussel sprouts, cauliflower, cabbage, rocket or arugula, watercress and horse radish, they added.
Broccoli, however, has a particularly powerful type of the compound called sulforaphane, which the researchers think gives the green vegetable an extra cancer-fighting kick, Richard Mithen, a biologist at Britain's Institute of Food Research said.
"When people get cancer some genes are switched off and some are switched on," he said. "What broccoli seems to be doing is switching on genes which prevent cancer developing and switching off other ones that help it spread."
Isothiocyanates (ITCs), which are perhaps the best studied, have been shown to provide protection against environmental carcinogen exposure by inducing detoxification pathways, thereby neutralizing potential carcinogens. These vegetables also contain indole-3-carbinol (I3C). Indole-3-carbinol has been shown to reduce the risk of breast cancer by decreasing estrogen activity.No doubt, green veggies are an important ally against cancer. Just check out: Diet, Chemotherapy, and the Truth: How to Win the War on Cancer.