Disease Proof

Lower Cholesterol Cuts Risk of Dementia

I’m demented already, so I might not be the best person to talk about this, but new research in the journal Dementia and Geriatric Cognitive Disorders claims keeping cholesterol levels in check, i.e. low, reduces your likelihood of Alzheimer's disease.

Between 1994 and 2007, a review of their medical records showed that 469 had Alzheimer's disease and 127 had vascular dementia, the second most common form of dementia after Alzheimer's disease, which is caused by clogged blood vessels and other conditions affecting the blood supply to the brain.

Compared to people with "desirable" cholesterol levels below 200 milligrams per deciliter of blood (mg/dL) in midlife, the risk of Alzheimer's disease three decades later was 57 percent higher in people with high midlife cholesterol levels of 240 mg/dL and above.

"Borderline" high cholesterol (200 to 239 mg/dL) tended to increase the risk of Alzheimer's disease as well, but the results were not statistically significant.

Or, you can just avoid problem altogether. A plant-based diet staves of heart disease and lowers blood pressure and cholesterol. Now, I think eating vegetables is better than going nuts—right?

Via Reuters.

Image credit: helgasms!

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Comments (3) Read through and enter the discussion with the form at the end
Manda - August 6, 2009 10:02 AM

I really wonder the effect of anti-hyperlipidemics had on these findings. Studies are starting to show that many commonly prescribed medications (cholesterol and bladder control meds) are causing dementia-like symptoms, and are often simply diagnosed as organic rather than drug related.

TruthorDeath - November 4, 2010 1:01 PM

"Now, I think eating vegetables is better than going nuts—right?"

Yah. Real cute Gerry. going nuts? are you serious? Alzheimer's disease is not 'going nuts'. How unnecessarily offensive.

And regarding cholesterol levels, total cholesterol is almost a completely worthless figure.

The ratio of HDL/LDL is more important, but the Trigs number is also a major factor. Typical LDL measuring does not take into account what KIND of LDL it is. Small dense particles are a far more accurate marker for CVD. If you have someone who has total cholesterol score of 200, with an LDL score of 100, HDL of 25, and Trigs of 75, their lipoprotein analysis will likely reveal that their LDL is mostly made up of small, dense particles. Now there you have a person with a potentially serious condition that needs to alter some things. But you could have someone who has a total cholesterol of 290, made up of 170 LDL, 80HDL, and 40 Trig. It's almost guaranteed that the LDL will be large "fluffy" particles, which DO NOT penetrate the cell walls to cause build up like the small particles do. High HDL and low Trigs are a key indicator for true cholesterol health. And do you know what the highest contributor to dangerously high Triglycerides is? High Carbs. Interesting, eh? Most people, including doctors, are clueless to this. Drug companies make waaaaaaaay too much coin off of the statins to trumpet this information.

So there you have it.
Follow mainstream dogma = Fail.
Research diligently = Win.

TruthorDeath - November 5, 2010 3:09 PM

Sorry. I forget to mention that I had already divided those Trig numbers by 5 to fit into the total cholesterol numbers. Technically, the Trigs in the 200 TC person would be 375 (75x5), but my point remains intact all the same. You can fool with the numbers in a spreadsheet all you want. You can have 290 TC made up of 200 LDL, 90 HDL, and 50 Trigs (trigs contribute 10 in this case). The bottom line is that high trigs and low HDL is almost gauranteed to be a warning sign, while high HDL and low VLDL production (low trigs) are generally considered markers for a healhty cardiovascular standing.

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