Obese People Have Sick Fat Cells

Alright, obesity is bad—that's common knowledge—but new research in Diabetes claims that fat people actually have “sick” fat cells that make insulin-resistant proteins. Krisha McCoy of HealthDay News reports:

The fat cells we found in our obese patients were deficient in several areas," study author Guenther Boden, the Laura H. Carnell Professor of Medicine and chief of endocrinology, said in Temple press release.

Boden said that the obese people's fat cells showed stress on the endoplasmic reticulum (ER), which helps cells synthesize proteins and monitor how they are folded. When the ER is stressed, Boden explained, it produces several proteins that ultimately lead to insulin resistance. Insulin resistance, in turn, plays a major role in the development of obesity-related conditions.

The differences in the fat cells between obese and lean people may help explain the link between obesity and a higher risk of diabetes, heart disease, and stroke, Boden theorized.

Certainly follows in line with what we already know about obesity and diabetes. As Dr. Fuhrman points out, extra body fat increases risk of type-2 diabetes, which screws up insulin and can eventually cause pancreatic poop out!

People need to eat more mushrooms—they can stop obesity! Speaking of obesity, rocker Ted Nugent recently called obese people vulgar and displeasing to look at. Eep!  

Stop Obesity, Eat Mushrooms!

Well, unless you like beef raised on potato chips, you might want to consider this report. New research in Appetite—cool name for a journal—claims mushrooms can help combat obesity; as a substitute for beef. Stephen Daniells of AP-FoodTechnology explains:

The researchers recruited 54 men and women to take part in the study and randomly assigned them to receive either beef or mushroom lunch entrées over four days – lasagna, napoleon, sloppy Joe and chili. Subjects then switched entrées to consume the other ingredient (mushroom or beef) the following week in order to act as their own controls.

The energy content of meat and mushroom lunches was 783 kcal and 339 kcal, respectively, while the portion size was held constant.

Lead researcher Lawrence Cheskin from John Hopkins Weight Management Center and co-workers report that total daily energy and fat intakes were significantly lower in the mushroom condition than the meat, while the subjects did not rate the palatability of the foods differently. Also ratings of appetite, satiation and satiety did not differ between the groups.

“We found that overtly substituting ground white button mushrooms for lean ground beef in a single meal for four consecutive days significantly reduced daily energy and fat intake, while maintaining ratings of palatability, appetite, satiation and satiety,” wrote the researchers.

“The method of substituting one food for another within familiar recipes may be more appealing to many prospective dieters than making more dramatic or restrictive changes in dietary behaviour.

Mushrooms are freaking incredible! Dr. Fuhrman also insists they are a great substitute for meat and you should eat them everyday. The problem is, too many Americans HATE mushrooms—sad, because mushrooms are also potent cancer-fighters.

Oh, and shrooms might save us from climate change too!
 

Fat Camp for the Whole Family

Patrons of a “weight-loss camp” in North Carolina and New York are finding that parents and kids can lose weight TOGETHER. Paul Smith of the Associated Press reports:

At the Adirondack camp, visiting family members join campers in the mornings for a long walk and at every meal. The rest of the time, parents attend classes on cooking, exercise and how to shop for healthy food. Siblings can tag along with campers to watch the daily activities.

"That had a big impression on her," Kelsey Galer said of her sister's visit to camp. "She just got a taste of my new lifestyle. We had spent a lot of time together (before camp), but it was never time like that -- being active and eating healthy."

The results of a three-year Wellspring survey of campers suggests that family support is beneficial, according to Daniel Kirschenbaum, Wellspring clinical director. The campers who reported having strong family support or used the post-camp program did better at maintaining or continuing to lose weight than those without strong support.

At the Wellspring camp in Pinehurst, North Carolina, about 60 miles southwest of Raleigh, parents join children between the ages of 5 and 14 for sessions that include sports, personal training and a spa.

Therapy is part of both programs to help people understand why they overeat and how to manage stress. Parents learn how to motivate their children to be healthy instead of discouraging them or emphasizing bad body image.

No doubt, families should get healthy together. Heck, we just found out kids will eat veggies if their parents do. Why not get your friends in the mix too?

Health Points: Monday 8.24.08

In a population-based, case-control study, the researchers matched 1,001 men with prostate cancer diagnosed between 2002 and 2005 with 942 age-matched cancer-free controls from King County, Washington.

No overall association was observed between the risk of prostate cancer and the current or past use of statin treatment. Duration of statin use was also not associated with prostate cancer risk.

"We also found no evidence that use of a statin was associated with risk of developing more aggressive subtypes of prostate caner," Stanford said in an interview with Reuters Health. "Overall we found no support for the current hypothesis that statin use may reduce risk of prostate cancer."

However, the results do suggest a significant increase in the risk of developing prostate cancer associated with current statin use and with longer durations of use among obese men (defined as a body mass index of 30 greater).

A team led by Linda Bartoshuk at the University of Florida in Gainesville surveyed 1300 people, 245 of whom had a history of ear infections, and found that among the over-30s, those who had suffered from ear infections were twice as likely to be obese as those with no such history. A subsequent analysis of four US medical databases confirmed the link. Those who had suffered from ear infections also rated fattier foods as 18 per cent more pleasurable than the others.

Infections may damage the chorda tympani taste nerve, which is stimulated at the front of the tongue and passes through the middle ear to the brain, says Bartoshuk. She says that the nerve normally inhibits some of the creamy sensations of fatty foods, as part of a response that inhibits tactile sensations that would otherwise make us gag. But nerve damage would lower this inhibiting effect, making foods seem creamier and so more pleasurable.

The postures, breathing and meditation included in the yoga intervention were "aimed at one common effect, i.e. 'to develop mastery over modifications of the mind' ... through 'slowing down the rate of flow of thoughts in the mind,'" the researchers explain.

Women in the yoga group also listened to lectures on using yoga to manage stress and other yoga-related topics, while those in the control group heard lectures on diet, exercise, the physiology of menopause, and stress.

After eight weeks, women in the yoga group showed a significant reduction in hot flashes, night sweats, and sleep disturbances, while the women in the control group did not, Dr. R. Chattha, of the Swami Vivekananda Yoga Anusandhana Samsthana in Bangalore, India, and colleagues found.

The state has given its 37,527 employees a year to start getting fit -- or they'll pay $25 a month for insurance that otherwise is free.

Alabama will be the first state to charge overweight state workers who don't work on slimming down, while a handful of other states reward employees who adopt healthy behaviors.

Alabama already charges workers who smoke -- and has seen some success in getting them to quit -- but now has turned its attention to a problem that plagues many in the Deep South: obesity.

The State Employees' Insurance Board this week approved a plan to charge state workers starting in January 2010 if they don't have free health screenings.

The American Academy of Pediatrics recommends that children devote no more than two hours per day to watching TV and playing video games.

Experts also encourage children to exercise regularly; some groups, including the AAP, recommend that boys move enough to take 13,000 steps each day, while girls should strive for 11,000. Another common recommendation is for children and teenagers to get at least one hour of moderate exercise on most, if not all, days of the week.

For the new study, researchers at Iowa State University in Ames looked at whether there were weight differences between children who met or did not meet recommendations for "screen time" and exercise.

They found that among 709 7- to 12-year-olds, those who did not meet either recommendation were three to four times more likely to be overweight than their peers who met both guidelines.

Both vaccines target the human papillomavirus, a common sexually transmitted virus that usually causes no symptoms and is cleared by the immune system, but which can in very rare cases become chronic and cause cervical cancer.

The two vaccines, Gardasil by Merck Sharp & Dohme and Cervarix by GlaxoSmithKline, target two strains of the virus that together cause an estimated 70 percent of cervical cancers. Gardasil also prevents infection with two other strains that cause some proportion of genital warts. Both vaccines have become quick best sellers since they were licensed two years ago in the United States and Europe, given to tens of millions of girls and women.

“Despite great expectations and promising results of clinical trials, we still lack sufficient evidence of an effective vaccine against cervical cancer,” Dr. Charlotte J. Haug, editor of The Journal of the Norwegian Medical Association, wrote in an editorial in Thursday’s issue of The New England Journal. “With so many essential questions still unanswered, there is good reason to be cautious.

According to the data, women's life expectancy saw a significant decline in 180 counties between 1983 and 1999. The cause for this precipitous drop? The folks at Women's Health attribute it to chronic diseases associated with obesity, smoking, and high blood pressure.

Here is a quick look at the U.S. counties that have experienced the greatest drop (numbers measured in years of average decline in female life expectancy):

Pulaski County, VA - 5.8
Radford, VA - 5.8
Dolores County, CO - 3.3
Montezuma County, CO - 3.3
San Juan County, CO - 3.3.
East Feliciana Parish, LA - 3.2
St. Helena Parish, LA - 3.2
West Feliciana Parish, LA - 3.2
Callaway County, MO - 3.0
Danville, VA - 3.0

Ted Nugent has never been one to beat around the bush so why should he stop now. Honestly I respect the man for the way he is willing and quick to speak his mind, but sometimes he’s a bit too blunt about things. Old Uncle Ted was on Anthony Bourdain’s No Reservations show on The Travel Channel where he was exploring the elements of Southwestern cuisine and stopped by Ted Nugents ranch in Texas. Anthony and Ted were speaking on many things to include Obesity. The Nuge’ said “Obesity is a manifestation of a cultural depravation in its most vulgar and displeasing-to-look-at form. And it’s suicide as a lifestyle.” Nugent also added “It all comes back to the horror, the soullessness of a trend in America that is the abandonment of parenting. Somebody’s got to go, ‘You can’t eat that. You’re way too fat.‘”

While I can understand what Ted is saying, Obesity is more than just an image issue. The last part of his statement is true that it may lead to certain and early death, but I think someone needs to give this guy a lesson in tact.

United States: Fat, Getting Fatter

In July the CDC reported that states like Mississippi, West Virginia, Alabama, and Louisiana continue to lead the nation in obesity. And now people are beginning to think that all the public initiatives to curb obesity are missing the mark. More from Dan Childs of ABC News:

The discouraging trends, reported in the fifth annual "F as in Fat: How Obesity Policies Are Failing in America, 2008" report from the Trust for America's Health (TFAH) and the Robert Wood Johnson Foundation (RWJF), reveal that obesity rates rose in 37 states in the past year, while no state registered a decrease in obesity.

Worse, in 24 states the uptick continued a trend seen from the previous year. Obesity rates rose for a third consecutive year in a total of 19 states.

"Our analysis found that on the state and community levels, overall we are not treating the obesity epidemic with the urgent response it deserves," said Jeff Levi, executive director of TFAH, during a Tuesday morning press conference…

… The new numbers suggest the continuation of a steady trend toward obesity that has been seen over the past several decades. In 1980, the report notes, the national average of obese adults was a mere 15 percent. Today, according to figures from the U.S. Centers for Disease Control and prevention, about a third of adults are obese.

With the increase in obesity has come a spike in the diseases associated with excess weight. According to the report, rates of type 2 diabetes -- a disease typically associated with obesity -- grew in 26 states last year.

Levi said the spike in such diseases carries a financial burden as well.

"Obesity is not just about health; it has a real impact on our country's economy as well," he said.

Maybe it’s falling on deaf ears, but obesity has been shown to increase cancer, diabetes, and death-risk. And the socio-economic impact is no joke either. Imagine being barred from a nightclub because you’re too fat—via Diet-Blog.

Obesity DOESN'T Harm the Heart?

Here’s an odd article. New research in the Archives of Internal Medicine suggests being obese may not elevate heart risks. The Associated Press investigates:

The results also show that stereotypes about body size can be misleading and that even "less voluptuous" people can have risk factors commonly associated with obesity, said study author MaryFran Sowers, a University of Michigan obesity researcher.

"We're really talking about taking a look with a very different lens" at weight and health risks, Sowers said.

In the study, about 51 percent of overweight adults, or roughly 36 million people nationwide, had mostly normal levels of blood pressure, cholesterol, blood fats called triglycerides and blood sugar.

Almost one-third of obese adults, or nearly 20 million people, also were in this healthy range, meaning that none or only one of those measures was abnormal.

Yet about a fourth of adults in the recommended-weight range had unhealthy levels of at least two of these measures. That means 16 million of them are at risk for heart problems.

It's no secret that thin people can develop heart-related problems and that fat people often do not. But that millions defy the stereotypes will come as a surprise to many people, Sowers said.

Not sure we want to float this kind of information out there. Americans are already fat enough. And according to this report, obesity and clumsiness could go hand in hand—via Reuters.

Eating Beans Keeps You Slim...

And, they help you make wonderful music! But seriously, That’sFit passes along some info on beans’ fiber-full powers. Here’s a snippet:

Beans. The more you eat, the ... less you weigh. That's what science says, that bean-eaters weigh less on average than non-bean-eaters. About 6.6 pounds less, to be exact.

RealAge expert John La Puma, MD, author of ChefMD's Big Book of Culinary Medicine, says it makes sense that beans have the power to knock off a few pounds. They are full of fiber, full of protein, and low in fat. This means they'll keep you fuller longer and will make only a small dent in your calorie intake.

Dr. Fuhrman considers beans—also called legumes—are serious health foods. Check it out:

A large recent study examined the eating habits of 32,000 adults for six years and then watched the incidence of cancer for these subjects over the next six years. Those who avoided red meat but at white meat regularly had a more than 300 percent increase in colon cancer incidence.1 The same study showed that eating beans, peas, or lentils, at least twice a week was associated with a 50 percent lower risk than never eating these foods. Beans, in general, not just soy, have additional anti-cancer benefits against reproductive cancers, such as breast and prostate cancer.2

And not only are beans packed with fiber, but they’re also loaded with protein. More from Dr. Fuhrman:

Eating more plant protein is the key to increasing our micronutrient intake. It is interesting to note that foods such as peas, green vegetables, and beans have lots of protein—even more protein per calorie than meat. But what is generally considered is that foods that are rich in plant protein are generally the foods that are richest in nutrients and phytochemicals. By eating more of these high-nutrient, low-calorie foods, we get plenty of protein, and our bodies get flooded with protective micronutrients simultaneously. Animal protein does not contain antioxidants and phytochemical; plant protein does. Plus, animal protein is married to saturated fat. Excesses of saturated fat are not favorable to good health.

Although, not everyone is excited about beans—like this little girl. Take a look:


Now, for more on beans and healthy bodyweight, don’t forget about this post: Beans and Obesity Prevention.


Continue Reading...

Health Points: Tuesday

With 23 percent of British children now considered overweight or obese, parents have increasing difficulty judging whether their own child is too heavy and most consider their overweight children normal, Ivan Lewis, the British health minister, warned. The letters home are designed as an early wake-up call, aimed at helping kids avoid later health problems, including diabetes and heart disease.

Starting next month, about 1.2 million British kindergartners and children in their last year of primary school will be weighed and notes about their weight mailed home, school and health officials said.

To avoid stigma, all parents—not just those of the overweight—will get an assessment of their child. And to avoid offense, the letters will avoid the use of "obese" or "fat," substituting instead "overweight" or "very overweight."
The recall is of beef prepared for shipment to retailers but not yet cut up in supermarket sized portions.

The recall is "Class 1," meaning there is a "reasonable probability" that eating the beef "will cause serious, adverse health consequences or death," the USDA said. It is the most dangerous level of the three classes of recall.

USDA's Food Safety and Inspection Service said the beef was sent to processing establishments and retail stores across the United States and had been produced June 17, June 24 and July 8.

The recall is of primal and subprimal cuts that are larger sections of cows, such as chuck and rib, that can be cut down for individual or family-sized packaging. It also is of "boxed beef" or carcasses that have been partially disassembled for shipping.
There is little dispute that bisphenol A can disrupt the hormonal system, but scientists differ on whether the very low amounts found in food and beverage containers can be harmful.

The National Toxicology Program, a partnership of federal health agencies, said in a recent draft report that there is "some concern" that the chemical can cause changes in behavior and the brain, and that it may reduce survival and birth weight in fetuses. The conclusion was based on animal studies.

However, the Food and Drug Administration's associate commissioner for science, Dr. Norris Alderson, told Congress in June that there was no reason for consumers to stop using products that contain the chemical.

Despite the uncertainty, consumer concern has prompted some governments and retailers to act.
A report from Brigham Young University shows only 36 percent of babies are breast-fed through six months. The American Academy of Pediatrics recommends breast-feeding through the first year.

The data are based on a weighted sample of more than 60,000 children, collected from national immunization surveys compiled by the Centers for Disease Control and Prevention. Although the data are focused on childhood immunization rates, questions also were asked about breast-feeding, giving the researchers a representative sample of nursing patterns in the United States.

The researchers found that children who were most likely to be breast-fed for more than six months typically had mothers with higher levels of education and income. Married women and those who lived in Western states were also more likely to breast-feed. Hispanic women and women born in other countries were also more likely to breast-feed.

Returning to work, being a smoker or living in the Northeast decreased the likelihood of long-term breast-feeding. Notably, low-income women who participated in the subsidized Women, Infants and Children program, which provides food, milk and formula to mothers and young children, were also more likely to stop breast-feeding sooner.
Wright is not an exotic dancer in a strip club. She's a 38-year-old mother of two from Atlanta, Georgia, looking to get in a decent workout.

"It works the abs, oh my goodness, muscles I didn't even know I had," Wright chuckled.

On this night, Wright is among more than a dozen women of all shapes and sizes -- no men allowed -- attending a beginner class at PoleLaTeaz, an Atlanta dance studio owned by Angela Edwards.

"We get preachers' wives, teachers, nurses, accountants, lawyers, anyone between the age of 18 and 70," Edwards said. "It's not boring...you get to wear fun clothes, listen to good music...and release your inner sexpot."

If online listings across the country are an indication, the popularity of pole dancing is spreading across the country from Southern California to Chicago to the Bible Belt.
Researchers say those strong feelings pro and con show in themselves that it will take a large study to see what, if anything, stretching really accomplishes. If stretching were remarkably effective, athletes would notice its effects right away and everyone would agree on when to stretch and what stretching does.

The study in Norway was the inspiration of Dr. Andy Oxman, a senior scientist at the Norwegian Knowledge Center for the Health Services. He had just completed what he calls a public clinical trial. It was a sort of reality show on public television that asked whether the nutritional supplement Valerian helped with insomnia; 405 people signed up to receive Valerian or a placebo and reported on their sleep by logging onto a Web site. Some participants insisted that because they slept so well they were taking Valerian. Or they said they knew they had taken the placebo because their sleep didn’t improve.

Then, the results were announced on the TV show and published: Valerian had little or no effect on sleep. Some who maintained they had the supplement actually had the placebo and vice versa.
Yet many people are not getting enough vitamin D, which the skin makes naturally when exposed to sunlight. A nationwide survey found that 41 percent of men and 53 percent of women in the United States were not getting enough of this vital nutrient.

"The importance of vitamin D may be underappreciated," said lead author Dr. Michal Melamed, a clinical fellow at Johns Hopkins University. "There are studies that link low vitamin D levels to the development of heart disease, peripheral arterial disease, diabetes, hypertension and different cancers," she said.

The report was published in the Aug. 11 online edition of the Archives of Internal Medicine.

For the study, Melamed's team collected data on more than 13,000 men and women who took part in the Third National Health and Nutrition Examination Survey. Levels of vitamin D were collected in 1988 and 1994, and the participants were followed through 2000.
Nebraska Beef, an Omaha meat packer, has been linked to two separate outbreaks of E. coli O157:H7 in the past two months. The first triggered a ground beef recall by Kroger's supermarkets. The second outbreak kicked off a ground beef recall by Dorothy Lane Market, a small chain in Ohio. The U.S. Department of Agriculture and the Centers for Disease Control and Prevention consider these two separate outbreaks because they involve two genetically distinct strains of O157:H7.

Whole Foods initiated the recall after Massachusetts health officials investigating a cluster of E. coli illnesses discovered all seven victims had bought meat at Whole Foods. The chain pulled ground beef from some of its stores on Wednesday. The Nebraska Beef recall was announced late Friday night.

My colleague Ylan Mui and I have gotten some comments from people who noted that the natural food chain is telling folks no contaminated Whole Foods meat has been found yet and we reported that in our story on Sunday. But before anyone is lulled into some false sense of security, there is other microbiological evidence linking Whole Foods to the outbreak.

Heart Disease, Doctors Failing Patients...


Perhaps the understatement of the century! Research from Outcomes, Inc., a Birmingham Alabama-based research firm, have determined that doctors often come up short when it comes to heart disease-prevention. Via Reuters Health:
Lead researcher Dr. Hamidreza Doroodchi and colleagues sent a survey on cardiovascular disease management to a random sample of 12,000 U.S. family physicians and general internists. A total of 888 completed the survey, which contained "case vignettes" for managing adults deemed to be at low or high risk of heart disease.

The study found that in the hypothetical case of a low-risk 45-year-old woman, only 28 percent of family doctors and 37 percent of internists made the "guideline-based preventive choice" of prescribing no aspirin or other antiplatelet therapy -- drugs that help prevent blood clots by keeping platelet blood cells from clumping together. The majority indicated that they would prescribe a daily aspirin for such a patient to reduce the risk of heart attack.

When asked whether they would start drug therapy to combat abnormal cholesterol levels, 51 percent of doctors said they would not do so in this low-risk patient -- which is in accordance with guidelines. On the other hand, 41 percent said they would prescribe a statin.

When it came to basic lifestyle advice, which is appropriate for low- and high-risk patients alike, doctors often fell short.

For example, while experts recommend that all adults limit their intake of artery-clogging trans fats, over one-third of doctors in the survey failed to recommend this measure for the low-risk 45-year-old woman.
A lot of it probably has to do with ignorance or the unwillingness to defy conventional medical thinking. More from Dr. Fuhrman:
For most people, illness means putting their fate in the hands of doctors and complying with their recommendations — recommendations that typically involve taking drugs for the rest of their lives while they watch their health gradually deteriorate. People are completely unaware that most illnesses are self-induced and can be reversed with aggressive nutritional methods.

Both patients and physicians act as though everyone’s medical problems are genetic, or assumed to be the normal consequence of aging. They believe that chronic illness is just what we all must expect. Unfortunately, the medical-pharmaceutical business has encouraged people to believe that health problems are hereditary and that we need to swallow poisons to defeat our genes. This is almost always untrue. We all have genetic weaknesses, but those weaknesses never get a chance to express themselves until we abuse our body with many, many years of mistreatment. Never forget, 99 percent of your genes are programmed to keep you healthy. The problem is that we never let them do their job.
I find that the problem gets even more out of whack when the doctors, nurses and other healthcare professionals are they themselves overweight or unhealthy. Makes you think that the whole system is mucked up—I wanted to use another word here.

New Obesity Research...


The infants were considered overweight if they had a body mass index (BMI) above the 85th weight-for-height percentile on 2 or more measurements taken at least 3 months part. This means that 85 percent of children their age and gender have a lower BMI, which is a measure of weight in relation to height.

In the first study, the researchers found that infants between the 85th and 94th weight-for-height percentiles actually had fewer hospital admissions and repeat admissions than normal-weight infants. However, higher than expected admission rates were seen in the most overweight infants (95th or higher percentile).

In the second study, overweight infants were more likely than their normal-weight peers to have developmental delays and snoring. There was also evidence that asthma and other breathing problems were more common in overweight infants.
According to the researchers, patients who were overweight or obese were less likely to die during follow up compared to their normal-weight peers. Being overweight or obese "remained protective" against death in a "risk-adjusted" analysis.


Heart failure patients who had a normal weight or who were underweight had the highest death rates. "It remains unknown, however, if higher body fat levels are actually the cause of better outcomes in patients with heart failure," the researchers note in the American Heart Journal.

"We believe there is a need for prospective studies to confirm these findings and elucidate potential mechanisms" for the potentially protective effect of increased body weight on heart failure, Oreopoulos and colleagues conclude.
The study, conducted by Dr. Erin J. Maher, from Casey Family Programs in Seattle, and colleagues, involved nearly 16,000 first-time kindergartners who had or had not been enrolled in childcare, defined as spending at least 10 hours per week in care not provided by a parent.


Childcare was subdivided into four types: 1) paid or unpaid care by a relative, friend, or neighbor, held at least occasionally at the child's home; 2) paid care by a non-relative family outside the child's home; 3) Head Start; and 4) care at daycare center, nursery school, preschool, or pre-kindergarten. Children were considered to be obese if their weight was in the 95th or higher percentile for height.

Overall, kids in childcare were more likely to obese than children not in childcare. Of the various childcare types, care by a relative, friend, or neighbor was most strongly linked to obesity. Compared with other racial groups, white children were less likely and Latino children more likely to be obese.