Early Exposure to Pesticide: Revisited

Last month DiseaseProof.com examined whether or not consuming organic food is safer than eating standard produce that may contain pesticide residue. In Disease Proof Your Child Dr. Fuhrman explains this only represents a negligible risk and that the real concern should be with early exposure to chemical cleaners, insecticides, weed killers, and compounds used in pressure-treated wood. These materials can cause a myriad of health problems including cancers such as leukemia.

Recently FoodConsumer.org published an article written by David Liu Ph.D. supporting the claim that household insecticides are linked to childhood leukemia. Dr. Liu cites a new French study:

In the case-control study, Florence Menegaux, Ph.D. of INSERM (France's national institute for medical research) and colleagues compared the cases with 288 matched controls that did not have diagnosed cancer.

The mothers in both groups were interviewed for exposure to insecticides during pregnancy and early years of their children. Their socioeconomic status, education, family medical history, and their child's pre and postnatal characteristics were surveyed. The hazard risk factors included gardening chemicals, fertilizer, herbicides, insecticides, and fungicides, among others…

…Exposure to insecticides in the garden during childhood was also linked with a nearly doubled risk of acute leukemia. Considering exposure to gardening insecticides both in childhood and during pregnancy, the risk was 20 percent higher than controls.

Exposure to bug spray at home during pregnancy and childhood was associated with a doubled risk of acute leukemia.

Exposure to both garden insecticide and fungicide during childhood was also associated with a more than doubled risk.

The toxins associated with conventional produce are hardly the only ones worth limiting. (More on that from the previous post about organic food.) In his book Eat to Live Dr. Fuhrman explains why residue on produce shouldn't be your chief concern:

The effects of ingesting pesticides in the very small amounts present in vegetation are unknown. Bruce Ames, Ph.D., director of the National Institute of Environmental Health Sciences Center at the University of California at Berkeley, who has devoted his career to examining this question, believes these minute amounts pose no risk at all.

He and other scientists support this view because humans and other animals are exposed to small amounts of naturally occurring toxins with every mouthful of organically grown, natural food. The body normally breaks down self-produced metabolic wastes and naturally occurring carcinogens in foods, as well as pesticides, and excretes these harmful substances every minute. Since 99.99 percent of the potential carcinogenic chemicals consumed are naturally present in all food, reducing our exposure to the 0.01 percent that are synthetic will not reduce cancer rates.

These scientists argue that humans ingest thousands of natural chemicals that typically have a greater toxicity and are present at higher doses than the very minute amount of pesticide residue that remains on food. Furthermore, animal studies on the carcinogenic potential in synthetic chemicals are done at doses a thousand-fold higher than what is ingested in food. Ames argues that a high percentage of all chemicals, natural or not, are potentially toxic in high doses—"the dose makes the poison"—and that there is no evidence of possible cancer hazards from the tiny chemical residue remaining on produce.

Dr. Fuhrman: Drugs Won't Solve Obesity Epidemic

Stephanie Saul of The New York Times reports that two new approaches to the nation's obesity epidemic are coming up for review by the Food and Drug Administration. Sanofi-Aventis will launch a prescription appetite blocker called Acomplia and GlaxoSmithKline is proposing an over-the-counter version of the weight loss drug Xenical, which will be renamed Alli. As Saul reports, overweight individuals are excited about the drugs despite the health risks of previous weight loss medications:

"I think if we could get obesity treatments to a situation like cholesterol where there are several different products, where one or two in combination might be successful, at least that would arm physicians with more than they have now," said Morgan Downey, executive director of the American Obesity Association, a patients' advocacy group in Washington.

The Food and Drug Administration has scheduled an advisory panel hearing for Jan. 23 to review Alli. And the F.D.A. could make its decision on Acomplia as soon as next month.

Both drug companies are seeking approval in a difficult regulatory environment, as the F.D.A. is moving cautiously in the wake of the Vioxx debacle. Any diet drug is up against a backdrop of safety issues from the past - most notably problems with the diet drug combination fen-phen. Fenfluramine, the "fen" half of the combination, was withdrawn from the market in 1997 after it was found to cause heart damage.

Xenical has shown itself to be moderately effective and has a long safety record. But Alli - a name the company has proposed because the drug must be allied with a weight-loss program - faces the higher hurdle required when prescription drugs are proposed for sale without a doctor's oversight. "You have to not only provide data that shows it's safe, you have to show that it's safe when it's misused," said Gerald Meyer, a former F.D.A. associate commissioner.

Can't wait for the FDA to rule? Consider this excerpt taken from Dr. Fuhrman's book Eat to Live:
New drugs are continually introduced that attempt to lessen the effects our nation's self-destructive eating behavior. Most often, our society treats disease after the degenerative illness has appeared, an illness that is the result of from forty to sixty years of nutritional self-abuse.

Drug companies and researchers attempt to develop and market medications to stem the obesity epidemic. This approach will always be doomed to fail. The body will always pay a price for consuming medicines, which usually have toxic effects. The "side" effects are not the only toxic effect of medications. Doctors learn in their introductory pharmacology course in medical school that all medications are toxic in varying degrees, whether side effects are experienced or not. Pharmacology professors stress never to forget that. You cannot escape the immutable biological laws of cause and effect through ingesting medicinal substances.

If we don't make significant changes in the foods we choose to consumer, taking drugs prescribed by physicians will not improve our health or extend our lives. If we wish true health protection, we need to remove the cause. We must stop abusing ourselves with disease-causing foods.

Tuesday Health Notes